Evidence map›Paper›PMID 28492053›Full record

ArticleInternational journal of women's dermatology2017

Association of ethnicity, Fitzpatrick skin type, and hirsutism: A retrospective cross-sectional study of women with polycystic ovarian syndrome.

L Afifi, L Saeed, L A Pasch, H G Huddleston, M I Cedars, L T Zane, K Shinkai

Open access · goldAbstract read
In one paragraph

Article in International journal of women's dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Gender diversity in adolescents with polycystic ovary syndrome.Journal of pediatric endocrinology & metabolism : JPEM · 2022
    Article
  11. Hirsutism, Normal Androgens and Diagnosis of PCOS.Diagnostics (Basel, Switzerland) · 2022
    Review
  12. Practical Approach to Hyperandrogenism in Women.The Medical clinics of North America · 2021
    Review
  13. Addressing important knowledge gaps about the disease burden of hirsutism.International journal of women's dermatology · 2021
    Article
  14. Article
  15. Assessment of Optimism in Women with Polycystic Ovary Syndrome: A Case Control-Study.International journal of environmental research and public health · 2021
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

L AfifiDepartment of Dermatology, University of California, San Francisco, CA.
L SaeedDepartment of Dermatology, University of California, San Francisco, CA.
L A PaschDepartment of Psychiatry, University of California, San Francisco, CA.
H G HuddlestonDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA.
M I CedarsDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA.
L T ZaneAnacor Pharmaceuticals, Palo Alto, CA.
K ShinkaiDepartment of Dermatology, University of California, San Francisco, CA.
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe complex interplay between ethnicity, Fitzpatrick skin type (FST), and hirsutism in patients with polycystic ovarian syndrome (PCOS) is poorly understood.

objectiveIn this cross-sectional, retrospective analysis, we examined the prevalence, severity, and distribution of hirsutism with clinician-rated site-specific and total modified Ferriman-Gallwey (mFG) visual scoring in a diverse cohort of American patients with PCOS.

methodsIndependent analyses were conducted on the basis of patient-reported FST ratings and ethnicity.

resultsIn this PCOS cohort, a correlation was found between hirsutism and ethnicity and the highest prevalence of hirsutism and total mFG scores was observed in Hispanic, Middle Eastern, African American, and South Asian patients. A positive correlation between hirsutism and FST was also observed with an increasing prevalence of hirsutism in the group of patients with higher FSTs. Significant trends in the anatomic distribution of hirsutism were observed between ethnic groups as well. A higher facial mFG score was found in African American patients but higher mFG scores in the truncal and extremity regions were observed in Middle Eastern patients. Truncal hirsutism was also associated with higher FSTs.

conclusionsEthnicity and FST may be important variables in both the quantitative and qualitative presentations of hirsutism in women with PCOS and should be considered in the diagnostic evaluation of any patient who is suspected of having the condition. Previously published studies that examined ethnicity, FST, and hirsutism in homogeneous cohorts limited comparison and generalizability but the strength of this study lies in its detailed analysis within a single large and diverse PCOS cohort. Validated studies are needed to determine whether clinical criteria for hirsutism should be adjusted for ethnicity and FST in the PCOS population and particularly within diverse cohorts and patients of mixed ancestry.

Indexed as

ethnicityFitzpatrick skin typehirsutismhyperandrogenismmodified Ferriman-GallweyPCOS

Identifiers

PMID28492053
PMCPMC5419030
OpenAlexW2596307093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.