ReviewInternational journal of women's dermatology2016
Vaginal rejuvenation using energy-based devices.
Review in International journal of women's dermatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Trial for the Evaluation of Efficacy and Safety of Votiva for Vaginal Rejuvenation
Non-ablative Diode Laser Therapy for Genitourinary Syndrome of Menopause: A Prospective Study on Efficacy, Safety, and Quality of Life and Sexuality Impact
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Vaginal lasers for treating stress urinary incontinence in women.The Cochrane database of systematic reviews · 2025Pooled it
- Impact of fractional COLasers in medical science · 2026Trial
- Efficacy of non-ablative vaginal erbium laser for rUTI prevention in postmenopausal women.Lasers in medical science · 2025Trial
- Effect of Transcutaneous Tibial Nerve Stimulation in Multiparous Egyptian Women with Vaginal Laxity: A Randomized Controlled Trial.Archives of sexual behavior · 2025Trial
- Efficacy of a Mixed Wavelength Laser for Vaginal Health in Postmenopausal Women: A Randomized Controlled Trial.International journal of women's health · 2025Trial
- Randomized clinical trial of vaginal microbiota in menopausal genitourinary syndrome using radiofrequency and topical estriol.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Trial
- Vaginal erbium laser for treatment of stress urinary incontinence: optimization of treatment regimen for a sustained long-term effect.Lasers in medical science · 2022Trial
- Comparative effects of fractional radiofrequency and microneedling on the genitalia of postmenopausal women: Histological and clinical changes.Clinics (Sao Paulo, Brazil) · 2022Trial
- Treatment to External Labia and Vaginal Canal With CO2 Laser for Symptoms of Vulvovaginal Atrophy in Postmenopausal Women.Aesthetic surgery journal · 2019Trial
- Modern methods of treating vaginal dryness and atrophy.Przeglad menopauzalny = Menopause review · 2026Review
- Iatrogenic Menopause and Severe Sexual Health Disruption Following Chemoradiotherapy: The Role of Natural-Origin Polynucleotides.International journal of women's health · 2025Article
- Chemical Biostimulation of Labial Majora: First Clinical Insights.Clinical, cosmetic and investigational dermatology · 2025Article
- Antimicrobial activity ofPeerJ · 2025Article
- Vaginal health in breast cancer survivors: a practical clinical approach.Therapeutic advances in medical oncology · 2025Review
- Bipolar Radiofrequency and Non-Crosslinked Hyaluronic Acid Plus Calcium Hydroxyapatite in the Treatment of Stress Urinary Incontinence.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Vaginal COBMC cancer · 2023Article
- Experimental Analysis of Vaginal Laxity in Rats Treated With a Combination of Er:YAG Fractional Lasers and AMSC-MP.Journal of lasers in medical sciences · 2023Article
- Hyaluronic Acid and Radiofrequency in Patients with Urogenital Atrophy and Vaginal Laxity.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Micro-Focused Ultrasound Therapy in Patients with Urogenital Atrophy and Vaginal Laxity.Journal of clinical medicine · 2022Article
- The ThermiVa In Genital Hiatus Treatment (TIGHT) Study.Sexual medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physiologic changes in a woman's life, such as childbirth, weight fluctuations, and hormonal changes due to aging and menopause, may alter the laxity of the vaginal canal, damage the pelvic floor, and devitalize the mucosal tone of the vaginal wall. These events often lead to the development of genitourinary conditions such as stress urinary incontinence; vaginal atrophy; dryness; and physiologic distress affecting a woman's quality of life, self-confidence, and sexuality. Various treatment modalities are currently available to manage these indications, varying from invasive vaginal surgery to more benign treatments like topical vaginal hormonal gels or hormone-replacement therapy. A new trend gaining momentum is the advent of energy-based devices for vaginal rejuvenation that apply thermal or nonthermal energy to the various layers of the vaginal tissue, stimulating collagen regeneration contracture of elastin fibers, neovascularization, and improved vaginal lubrication. This review aims to present the available technologies offering vaginal rejuvenation and the scientific evidence that underlines their safety and efficacy for this indication.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.