Evidence map›Paper›PMID 28491013›Full record

ArticleInternational journal of peptide research and therapeutics2017

Peptides with 6-Aminohexanoic Acid: Synthesis and Evaluation as Plasmin Inhibitors.

Maciej Purwin, Agnieszka Markowska, Irena Bruzgo, Tomasz Rusak, Arkadiusz Surażyński, Urszula Jaworowska, Krystyna Midura-Nowaczek

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of peptide research and therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Maciej PurwinDepartment of Organic Chemistry, Medical University of Bialystok, Mickiewicza 2A Str, 15-222 Białystok, Poland.
Agnieszka MarkowskaDepartment of Organic Chemistry, Medical University of Bialystok, Mickiewicza 2A Str, 15-222 Białystok, Poland.
Irena BruzgoDepartment of Organic Chemistry, Medical University of Bialystok, Mickiewicza 2A Str, 15-222 Białystok, Poland.
Tomasz RusakDepartment of Physical Chemistry, Medical University of Bialystok, Mickiewicza 2A Str, 15-222 Białystok, Poland.
Arkadiusz SurażyńskiDepartment of Medicinal Chemistry, Medical University of Bialystok, Mickiewicza 2A Str, 15-222 Białystok, Poland.
Urszula JaworowskaDepartment of Organic Chemistry, Medical University of Bialystok, Mickiewicza 2A Str, 15-222 Białystok, Poland.
Krystyna Midura-NowaczekDepartment of Organic Chemistry, Medical University of Bialystok, Mickiewicza 2A Str, 15-222 Białystok, Poland.
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fifteen new peptide derivatives of ɛ-aminocaproic acid (EACA) containing the known fragment -Ala-Phe-Lys- with an affinity for plasmin were synthesised in the present study. The synthesis was carried out a solid phase. The following compounds were synthesised: H-Phe-Lys-EACA-X, H-d-Ala-Phe-Lys-EACA-X, H-Ala-Phe-Lys-EACA-X, H-d-Ala-Phe-EACA-X and H-Ala-Phe-EACA-X, where X = OH, NH

Indexed as

6-Aminohexanoic acidAntifibrinolyticsPlasmin inhibitors

Identifiers

PMID28491013
PMCPMC5401710
OpenAlexW2521817367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.