Evidence map›Paper›PMID 28490888›Full record

ArticleOncoTargets and therapy2017

Maintenance therapy with all-trans retinoic acid and arsenic trioxide improves relapse-free survival in adults with low- to intermediate-risk acute promyelocytic leukemia who have achieved complete remission after consolidation therapy.

Bin Liang, Zhouyi Zheng, Yifen Shi, Jingjing Chen, Xudong Hu, Honglan Qian, Zhijian Shen, Songfu Jiang, Kang Yu, Jianhua Feng

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Maintenance Therapy in AML.Frontiers in oncology · 2020
    Review
  3. Article
  4. Article
  5. [Involvement of PML proteins in treatment of acute promyelocytic leukemia with arsenic trioxide].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2018
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Bin LiangDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Zhouyi ZhengDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Yifen ShiDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Jingjing ChenDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Xudong HuDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Honglan QianDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Zhijian ShenDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Songfu JiangDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Kang YuDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Jianhua FengDivision of Hematology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou.
Wenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, the optimal maintenance therapy for patients with acute promyelocytic leukemia (APL) who have achieved complete remission (CR) after completing consolidation chemotherapy remains controversial. The comparative effectiveness of the all-trans retinoic acid (ATRA) plus arsenic trioxide (As

methodsA retrospective review of 58 adult patients diagnosed with APL was conducted. After receiving consolidation therapy and achieving CR, 30 patients were administered maintenance therapy with an ATRA plus As

resultsGrade 3-4 neutropenia was significantly more frequent in the ATRA+chemotherapy group (N=9, 32.1%) than in the ATRA+As

conclusionMaintenance therapy with ATRA and As

Indexed as

acute promyelocytic leukemiaall-trans retinoic acidarsenic trioxidemaintenance therapysurvival

Identifiers

PMID28490888
PMCPMC5414635
OpenAlexW2608563678

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.