Evidence map›Paper›PMID 28490877›Full record

ArticleInternational journal of nanomedicine2017

Low-density lipoprotein-coupled micelles with reduction and pH dual sensitivity for intelligent co-delivery of paclitaxel and siRNA to breast tumor.

Wen-Jing Zhu, Shu-di Yang, Chen-Xi Qu, Qiao-Ling Zhu, Wei-Liang Chen, Fang Li, Zhi-Qiang Yuan, Yang Liu, Ben-Gang You, Xue-Nong Zhang

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Recent Development of LDL-Based Nanoparticles for Cancer Therapy.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
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  11. Review
  12. Article
  13. Theranostic small interfering RNA nanoparticles in cancer precision nanomedicine.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2020
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Nanotechnology for Cancer Therapy Based on Chemotherapy.Molecules (Basel, Switzerland) · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Wen-Jing ZhuDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Shu-di YangDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Chen-Xi QuDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Qiao-Ling ZhuDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Wei-Liang ChenDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Fang LiDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Zhi-Qiang YuanDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Yang LiuDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Ben-Gang YouDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
Xue-Nong ZhangDepartment of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou.
American Pharmacists Association · USSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multidrug resistance (MDR) is a major obstacle for the clinical therapy of malignant human cancers. The discovery of RNA interference provides efficient gene silencing within tumor cells for reversing MDR. In this study, a new "binary polymer" low-density lipoprotein-

Indexed as

AnimalsBreast NeoplasmsCell Line, TumorDrug CarriersDrug LiberationDrug Resistance, MultipleFemaleHumansHydrogen-Ion ConcentrationLipoproteins, LDLMCF-7 CellsMicellesMice, NudeOxidation-ReductionPaclitaxelPolymersDrug CarriersLipoproteins, LDLMicellesPaclitaxelPolymersRNA, Small Interferingco-deliveryenvironmentally sensitivemicellemultidrug resistancetumor targeting

Identifiers

PMID28490877
PMCPMC5413542
OpenAlexW2608334856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.