ArticleScientific reports2017
Multiple biomarker responses (serum biochemistry, oxidative stress, genotoxicity and histopathology) in Channa punctatus exposed to heavy metal loaded waste water.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
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- Phytogenic Immunostimulants: Evaluation of Antifungal and Immunomodulatory Effect of Basil and Lemongrass Extracts inACS omega · 2026Article
- Chronic toxicological impacts of tire rubber nanoparticles on hematobiochemical, oxidative stress, and immunological responses in Nile tilapia (Oreochromis niloticus).Fish physiology and biochemistry · 2026Article
- Time and contamination level dependence of metal bioaccumulation and multibiomarker responses in fish: implications for biomonitoring.Environmental monitoring and assessment · 2026Article
- Chronic cadmium exposure disrupts the gill-gut axis via oxidative and endoplasmic reticulum stress in juvenile Carassius auratus.Veterinary research communications · 2026Article
- Integrating hematological profile and biomarker analysis for metals and metalloids ecotoxicological assessment on Wallago catfish and Indian carp health in Head Siphon, Mailsi, Pakistan.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Fate and Effects of Heavy Metals in Fishes: Antioxidant Defense System, miRNA/Gene Expression Response, and Histopathological Reproductive Manifestations.Biological trace element research · 2025Review
- Ecotoxicological effects of heavy metal contamination on reproductive health and gamete quality in female Nile tilapia (Veterinary world · 2025Article
- Sublethal Concentrations of Cadmium and Lead: Effects on Hemato-Biochemical Parameters and Tissue Accumulation in Wallagu attu.Biological trace element research · 2025Article
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- Assessing the effects of cadmium on antioxidant enzymes and histological structures in rainbow trout liver and kidney.Scientific reports · 2024Article
- Nanoremediation of tilapia fish culture using iron oxide nanoparticles biosynthesized by Bacillus subtilis and immobilized in a free-floating macroporous cryogel.BMC veterinary research · 2024Article
- Identification ofAnimals : an open access journal from MDPI · 2024Article
- Oxidative stress, inflammation, and steatosis elucidate the complex dynamics of HgClScientific reports · 2024Article
- Assessing physiological responses and oxidative stress effects in Rhamdia voulezi exposed to high temperatures.Fish physiology and biochemistry · 2024Article
- Effects of Dietary Supplement of Basil Extract on Biochemical and Immunological Parameters and Growth Performance inAquaculture nutrition · 2024Article
- Heavy metal toxicity arising from the industrial effluents repercussions on oxidative stress, liver enzymes and antioxidant activity in brain homogenates of Oreochromis niloticus.Scientific reports · 2023Article
- Review
- Multi biomarker approach to assess manganese and manganese nanoparticles toxicity in Pangasianodon hypophthalmus.Scientific reports · 2023Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Experiments were conducted to investigate the health of fish Channa punctatus inhabiting heavy metal-loaded waste water. Heavy metals in the order of Fe > Mn > Zn > Co > Ni > Cu = Cr were present in the waste water. Gills had high metal load followed by liver and then kidney. Albumin, albumin to globulin (A:G) ratio, triglyceride, high density lipoprotein (HDL) and very low density lipoprotein (VLDL) were found to be lower but phospholipid, low density lipoprotein (LDL), total protein, lipid and cholesterol were higher as compared to the reference. Oxidative stress markers such as superoxide dismutase (SOD), catalase (CAT), glutathione S transferase (GST) and lipid peroxidation (LPO) were significantly higher in all tissues, whereas reduced glutathione (GSH) levels were comparatively low. Damage to DNA was observed with significantly higher mean tail length of comets in the exposed fish gill cells (30.9 µm) followed by liver (24.3 µm) and kidney (20.6 µm) as compared to reference fish (5.2, 4.8 and 5.9 µm respectively). Histopathology in gill, liver and kidney also showed marked damage. Integrated biochemical, oxidative stress, genotoxicity and histopathological findings are valuable biomarkers for native fish adaptive patterns, and monitoring of water quality/pollution of freshwater ecosystems.
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