Evidence map›Paper›PMID 28490769›Full record

ArticleScientific reports2017

Increased cerebral expressions of MMPs, CLDN5, OCLN, ZO1 and AQPs are associated with brain edema following fatal heat stroke.

Yu Du, Jing-Tao Xu, Hong-Nian Jin, Rui Zhao, Dong Zhao, Si-Hao Du, Ye Xue, Xiao-Li Xie, Qi Wang

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Forensic neuropathology in the past decade: a scoping literature review.Forensic science, medicine, and pathology · 2024
    Article
  5. Microglia polarization in heat-induced early neural injury.Archives of medical science : AMS · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. EPStem cells translational medicine · 2019
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Yu DuDepartment of Forensic Medicine, National Police University of China, Shenyang, China.
Jing-Tao XuDepartment of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Hong-Nian JinForensic Science Centre of Guangdong Provincial Public Security Department, Guangzhou, China.
Rui ZhaoDepartment of Forensic Pathology, China Medical University School of Forensic Medicine, Shenyang, China.
Dong ZhaoCollaborative Innovation Center of Judicial Civilization, China; Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, Beijing, China.
Si-Hao DuDepartment of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Ye XueDepartment of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, China.
Xiao-Li XieDepartment of Toxicology, School of Public Health, Southern Medical University, Guangdong Provincial Key Laboratory of Tropical Disease Research, Guangzhou, China. xiexiaoli1999@126.com.
Qi WangDepartment of Forensic Pathology, School of Forensic Medicine, Southern Medical University, Guangzhou, China. wangqi_legmed@126.com.
Southern Medical University · CNChina Medical University · CNCriminal Investigation Police University of China · CNSouth China Institute of Collaborative Innovation · CNZhejiang Provincial Public Security Department · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human brain samples were collected from 46 autopsy cases, including 23 fatal heat stroke cases and 23 age-matched controls. Nine candidate reference genes (PES1, POLR2A, IPO8, HMBS, SDHA, GAPDH, UBC, B2M, ACTB) were evaluated in the cerebral cortex of 10 forensic autopsy cases (5 heat stroke and 5 controls), using the geNorm module in qBase

Indexed as

AquaporinsBrainBrain EdemaClaudin-5FemaleGene Expression RegulationHeat StrokeHumansMaleMatrix MetalloproteinasesMiddle AgedOccludinReference StandardsReproducibility of ResultsRNARNA, MessengerAquaporinsClaudin-5Matrix MetalloproteinasesOccludinRNARNA, MessengerTJP1 protein, humanWaterZonula Occludens-1 Protein

Identifiers

PMID28490769
PMCPMC5431794
OpenAlexW2611309261

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.