Evidence map›Paper›PMID 28490424›Full record

ArticleClinical and vaccine immunology : CVI2017

Waning Immunity and Microbial Vaccines-Workshop of the National Institute of Allergy and Infectious Diseases.

Xin-Xing Gu, Stanley A Plotkin, Kathryn M Edwards, Alessandro Sette, Kingston H G Mills, Ofer Levy, Andrea J Sant, Annie Mo, William Alexander, Kristina T Lu and 1 more

Abstract readConference Proceedings
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Ultra-long-acting (XLA) antivirals for chronic viral hepatitis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. CD45RB Status of CD8Cell reports · 2020
    Article
  15. Review
  16. Vaccine-Induced CD8Frontiers in immunology · 2020
    Review
  17. Article
  18. Article
  19. A physician's guide to the 2-dose schedule of MenB-FHbp vaccine.Human vaccines & immunotherapeutics · 2019
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xin-Xing GuDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA guxx@niaid.nih.gov.
Stanley A PlotkinUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kathryn M EdwardsVanderbilt University, Nashville, Tennessee, USA.
Alessandro SetteLa Jolla Institute of Allergy and Immunology, La Jolla, California, USA.
Kingston H G MillsSchool of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.
Ofer LevyPrecision Vaccines Program, Boston Children's Hospital, Boston, Massachusetts, USA.
Andrea J SantUniversity of Rochester Medical Center, Rochester, New York, USA.
Annie MoDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
William AlexanderDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Kristina T LuDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Christopher E TaylorDivision of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the middle of the 20th century, vaccines have made a significant public health impact by controlling infectious diseases globally. Although long-term protection has been achieved with some vaccines, immunity wanes over time with others, resulting in outbreaks or epidemics of infectious diseases. Long-term protection against infectious agents that have a complex life cycle and antigenic variation remains a key challenge. Novel strategies to characterize the short- and long-term immune responses to vaccines and to induce immune responses that mimic natural infection have recently emerged. New technologies and approaches in vaccinology, such as adjuvants, delivery systems, and antigen formulations, have the potential to elicit more durable protection and fewer adverse reactions; together with

Indexed as

Immunity, CellularImmunity, HumoralAdjuvants, ImmunologicBacterial VaccinesDrug CarriersDrug Delivery SystemsEducationHumansMalaria VaccinesNational Institute of Allergy and Infectious Diseases (U.S.)Time FactorsUnited StatesViral VaccinesAdjuvants, ImmunologicBacterial VaccinesDrug CarriersMalaria VaccinesViral VaccinesadjuvantsBordetella pertussisimmunityinfluenzamalariamumpsNeisseria meningitidisSalmonellavaccines

Identifiers

PMID28490424
PMCPMC5498725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.