Evidence map›Paper›PMID 28490127›Full record

ArticleFood chemistry2017

Milk bioactive peptide database: A comprehensive database of milk protein-derived bioactive peptides and novel visualization.

Søren Drud Nielsen, Robert L Beverly, Yunyao Qu, David C Dallas

Abstract read
In one paragraph

Article in Food chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed.

  1. Artificial intelligence catalyzes antimicrobial peptide design.Synthetic and systems biotechnology · 2027
    Review
  2. Supplemented acetylated whey comparing to N-acetylcysteine exerted promising chelation activity for overload iron-induction lung injury in rats.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
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69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Søren Drud NielsenNutrition Program, School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, United States.
Robert L BeverlyNutrition Program, School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, United States.
Yunyao QuNutrition Program, School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, United States.
David C DallasNutrition Program, School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, United States. Electronic address: dave.dallas@oregonstate.edu.

Funding

Deciphering the function of naturally occurring peptides in human milkR00HD079561 · NICHD · OREGON STATE UNIVERSITY · PI DALLAS, DAVID CHARLES · 2016 to 2018
$741k
Deciphering the function of naturally occurring peptides in human milkK99HD079561 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DALLAS, DAVID CHARLES · 2014 to 2015
$157k
NICHD NIH HHS K99 HD079561NICHD NIH HHS R00 HD079561
6 · The paper itself

Abstract

During processing and digestion, milk proteins are disassembled into peptides with an array of biological functions, including antimicrobial, angiotensin-converting enzyme inhibition, antioxidant, opioid, and immunomodulation. These functions are summarized in numerous reviews, yet information on which peptides have which functions remains scattered across hundreds of research articles. We systematically searched the literature for all instances of bioactive peptides derived from milk proteins from any mammalian source. The data were compiled into a comprehensive database, which can be used to search for specific functions, peptides, or proteins (http://mbpdb.nws.oregonstate.edu). To review this large dataset, the bioactive peptides reported in the literature were visually mapped on the parent protein sequences, providing information on sites with highest abundance of bioactive peptides.

Indexed as

Milk ProteinsPeptidesAmino Acid SequenceAngiotensin-Converting Enzyme InhibitorsAnimalsMilkAngiotensin-Converting Enzyme InhibitorsMilk ProteinsPeptidesACECaseinDigestomeDPP-IVPeptidomicsWhey

Identifiers

PMID28490127
PMCPMC5486413

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.