ArticleNature2017
Discovery of nitrate-CPK-NLP signalling in central nutrient-growth networks.
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Article in Nature, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 279 papers.
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279citing papers in PubMed
106.9field-weighted citation impact, top 1% of its field
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Who cites it
279 citing papers in PubMed, 639 citations in OpenAlex.
- Review
- Beyond membrane transport: Transporters as dynamic signal integrators for plant signaling and adaptation.Plant communications · 2026Review
- Nitrate transiently rewires transcription in developing xylem of Populus wood to promote cell expansion via CRF4.The Plant cell · 2026Article
- Article
- CIPK11 Regulates Plant Adaptation to Nitrate Availability in Arabidopsis.Plants (Basel, Switzerland) · 2026Article
- Nonnodulating Fagales retain the functional NODULE INCEPTION gene.The New phytologist · 2026Article
- OsDUF1223 negatively regulates seedling drought tolerance and modulates nitrate-dependent root growth in rice.PLoS genetics · 2026Article
- Lateral Root Development: Molecular Mechanisms and Adaptive Regulation.Plant, cell & environment · 2026Review
- Evaluating Causal Claims in Plant Developmental Metabolism: A When-Where-How Framework.Plants (Basel, Switzerland) · 2026Review
- Natural variation in BRN1 enhances nitrogen sensitivity to improve rice nitrogen use efficiency.Nature communications · 2026Article
- Lily NIN-like transcription factor LlNLP7 confers thermotolerance and promotes growth.Molecular horticulture · 2026Article
- FaCPK19-FaTT1 axis decodes heat-induced CaThe New phytologist · 2026Article
- Nitrogen Status Rewires Transcriptional Regulation of Dhurrin, a Dual-Purpose Defense Metabolite inPlant direct · 2026Article
- Root Transporters Shape Rhizosphere Microbiomes to Enhance Nitrogen Acquisition Efficiency in Plants.Microorganisms · 2026Review
- Genome-wide analyses of NPF and NRT2 reveal a potential role for a key gene, CqNRT2.2, in the quinoa response to nitrate.BMC plant biology · 2026Article
- From signals to solutions: stress-induced leaf senescence and synthetic biology and AI approaches for crop resilience.Molecular horticulture · 2026Review
- Metabolic Enzyme MeHNL11 Regulates MeCAS1b Transcription for Cyanide Reutilization in Response to Nitrate Deficiency in Cassava.Plant biotechnology journal · 2026Article
- A plasma membrane Ca2+-dependent protein kinase PtCDPK2 promotes phosphorus starvation resilience in Phaeodactylum tricornutum.Journal of experimental botany · 2026Article
- The NRT1.1-NLP7 Nexus: An Integrative Signaling Nexus from Nitrate Sensing to Systemic Adaptation and Structure-Guided Engineering.Plants (Basel, Switzerland) · 2026Review
- The SPX protein family in plants: from phosphate sensors to multifunctional signaling hubs.Stress biology · 2026Review
219 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 4 countries.
Kun-Hsiang LiuDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Yajie NiuDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Mineko KonishiBiotechnology Research Center, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Yue WuDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Hao DuDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Hoo Sun ChungDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Lei LiDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Marie BoudsocqDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Matthew McCormackDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Shugo MaekawaBiotechnology Research Center, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Tetsuya IshidaBiotechnology Research Center, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Chao ZhangHoward Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, UCSF, 600 16th St, San Francisco, California 94143, USA.
Kevan ShokatHoward Hughes Medical Institute and Department of Cellular and Molecular Pharmacology, UCSF, 600 16th St, San Francisco, California 94143, USA.
Shuichi YanagisawaBiotechnology Research Center, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.
Jen SheenDepartment of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA.
Massachusetts General Hospital · USThe University of Tokyo · JPHoward Hughes Medical Institute · USUniversité Paris-Sud · FR
Funding
Glucose Signal Transduction Pathways in PlantsR01GM060493 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2000 to 2017
$5.7MSignaling Mechanisms in Plant Innate ImmunityR01GM070567 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2005 to 2017
$4.2MPlant Nutrient-Growth Signaling NetworkR01GM129093 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI SHEEN, JEN · 2018 to 2025
$2.8MNIGMS NIH HHS R01 GM060493NIGMS NIH HHS R01 GM070567NIGMS NIH HHS R01 GM129093
Abstract
Nutrient signalling integrates and coordinates gene expression, metabolism and growth. However, its primary molecular mechanisms remain incompletely understood in plants and animals. Here we report unique Ca
Indexed as
Signal TransductionAmidohydrolasesAmino Acid SequenceArabidopsisArabidopsis ProteinsBiomassCalciumCalcium-Binding ProteinsCalcium-Calmodulin-Dependent Protein KinasesCalcium SignalingCarbonCellular ReprogrammingFoodGene Expression Regulation, PlantNitratesNitrogenAmidohydrolasesArabidopsis ProteinsATCDPK1 protein, ArabidopsisCalciumCalcium-Binding ProteinsCalcium-Calmodulin-Dependent Protein KinasesCarbonCPK30 protein, ArabidopsisCPK32 protein, ArabidopsisNitratesNitrogenProtein Kinases
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.