Observational studyMedicine2017
Incidence and risk factors of depression after diagnosis of lung cancer: A nationwide population-based study.
Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Disparities in Depression Among Older Asian, Native Hawaiian, and Pacific Islander Patients With Lung Cancer.Cancer medicine · 2026Article
- Inflammation-associated depression in cholangiocarcinoma: impacts of surgical resection and radiotherapy.BioPsychoSocial medicine · 2026Article
- Psychosomatics at the threshold: cancer, mood disorders, and the mental pain of death - where precision medicine meets spirituality.Frontiers in psychiatry · 2026Article
- Article
- Risk of Anxiety and Depression after Diagnosis of Young-Onset Colorectal Cancer: A Population-Based Cohort Study.Current oncology (Toronto, Ont.) · 2022Article
- Serum tumor necrosis factor-α, interleukin-1β, interleukin-6, and interleukin-17 relate to anxiety and depression risks to some extent in non-small cell lung cancer survivor.The clinical respiratory journal · 2022Article
- Risk of major depressive disorder in Japanese cancer patients: A matched cohort study using employer-based health insurance claims data.Psycho-oncology · 2020Article
- Article
- Coping strategies and depressive symptoms in cancer patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020Observational
- Prevalence and factors associated with diagnosed depression among hospitalized cancer patients with metastatic disease.Social psychiatry and psychiatric epidemiology · 2020Article
- Stability of Symptom Clusters in Patients With Lung Cancer Receiving Chemotherapy.Journal of pain and symptom management · 2019Article
- "Age matters"-German claims data indicate disparities in lung cancer care between elderly and young patients.PloS one · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to explore the incidence and risk factors of depression after lung cancer diagnosis. Using the Taiwan National Health Insurance Research Database (NHIRD), incidences and risk factors of depression in lung cancer and nonlung cancer cohorts were analyzed.From 1998 to 2006, a total of 22,125 patients were included in each matched cohort of lung cancer and nonlung cancer patients from NHIRD. The incidence of depression was higher in the lung cancer cohort than in the nonlung cancer cohort (1545.8 vs 1366.6 per 100,000 person-years). An increased risk of depression was observed in the lung cancer cohort [adjusted hazard ratio (aHR): 1.16, 95% confidence interval (95% CI): 1.01-1.34, P = .0377]. In lung cancer patients, age ≤50 years (aHR: 2.72, 95% CI: 2.02-3.66, P < .0001), age 50 to 69 years (aHR: 2.34, 95% CI: 1.87-2.94, P < .0001), female gender (aHR: 1.50, 95% CI: 1.26-1.80, P < .0001), coronary artery disease (CAD) (aHR: 1.40, 95% CI: 1.08-1.82, P = .0113), and operation (aHR: 1.78, 95% CI: 1.46-2.16, P < .0001) were associated with an increased risk of depression. In addition, higher incidences of emergency room (ER) visit (4.76 vs 2.82, per person-year) and admission (5.73 vs 4.33, per person-year) were observed in lung cancer patients with depression than those without depression.Our results showed that early surveillance and intervention of depression should be advocated after a diagnosis of lung cancer.
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