Evidence map›Paper›PMID 28489528›Full record

ArticleeLife2017

Reciprocal synapses between mushroom body and dopamine neurons form a positive feedback loop required for learning.

Isaac Cervantes-Sandoval, Anna Phan, Molee Chakraborty, Ronald L Davis

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 107 citations in OpenAlex.

  1. The larvalScience advances · 2026
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  3. The larvalbioRxiv : the preprint server for biology · 2026
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  9. Compression-based inference of network motif sets.PLoS computational biology · 2024
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  10. Review
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  17. Rewarding Capacity of Optogenetically Activating a Giant GABAergic Central-Brain Interneuron in LarvalThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  18. Article
  19. Differential second messenger signaling via dopamine neurons bidirectionally regulates memory retention.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Isaac Cervantes-SandovalDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, United States.ORCID 0000-0002-6372-7288
Anna PhanDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, United States.
Molee ChakrabortyDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, United States.
Ronald L DavisDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, United States.ORCID 0000-0002-5986-7608
Scripps Research Institute · US

Funding

Biology of memoryR35NS097224 · NINDS · UNIVERSITY OF FLORIDA · PI DAVIS, RONALD L · 2017 to 2024
$9.1M
Olfactory memory trace formation in DrosophilaR01NS052351 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI DAVIS, RONALD L · 2006 to 2016
$4.2M
Molecular Biology of Drosophila Learning and MemoryR37NS019904 · NINDS · SCRIPPS FLORIDA · PI DAVIS, RONALD L · 2013 to 2016
$1.9M
NINDS NIH HHS R01 NS052351NINDS NIH HHS R35 NS097224NINDS NIH HHS R37 NS019904
6 · The paper itself

Abstract

Current thought envisions dopamine neurons conveying the reinforcing effect of the unconditioned stimulus during associative learning to the axons of

Indexed as

FeedbackLearningAnimalsConditioning, ClassicalDopaminergic NeuronsDrosophilaMushroom BodiesNerve NetSynapsesD. melanogasterdopaminergic neuronslearning and memorymushroom bodyneurosciencereciprocal connectivityrecurrent circuit

Identifiers

PMID28489528
PMCPMC5425253
OpenAlexW2613567252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.