Evidence map›Paper›PMID 28488690›Full record

ArticleEuropean journal of clinical nutrition2017

Soyfood and isoflavone intake and risk of type 2 diabetes in Vietnamese adults.

C T Nguyen, N M Pham, V V Do, C W Binns, V M Hoang, D A Dang, A H Lee

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Article in European journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

C T NguyenSchool of Public Health, Curtin University, Perth, WA, Australia.
N M PhamSchool of Public Health, Curtin University, Perth, WA, Australia.
V V DoSchool of Public Health, Curtin University, Perth, WA, Australia.
C W BinnsSchool of Public Health, Curtin University, Perth, WA, Australia.
V M HoangHanoi University of Public Health, Hanoi, Vietnam.
D A DangNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
A H LeeSchool of Public Health, Curtin University, Perth, WA, Australia.
Curtin University · AUNational Institute Of Hygiene And Epidemiology · VNHanoi University · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesAnimal studies have demonstrated that soy isoflavones exert antidiabetic effects. However, evidence regarding the association between soyfood intake, a unique source of isoflavones, and type 2 diabetes remains inconclusive. This study assessed the relationship between habitual intakes of soyfoods and major isoflavones and risk of type 2 diabetes in Vietnamese adults. SUBJECTS/

methodsA hospital-based case-control study was conducted in Vietnam during 2013-2015. A total of 599 newly diagnosed diabetic cases (age 40-65 years) and 599 hospital-based controls, frequency matched by age and sex, were recruited in Hanoi, capital city of Vietnam. Information on frequency and quantity of soyfood and isoflavone intake, together with demographics, habitual diet and lifestyle characteristics, was obtained from direct interviews using a validated and reliable questionnaire. Unconditional logistic regression analyses were performed to examine the association between soy variables and type 2 diabetes risk.

resultsHigher intake of total soyfoods was significantly associated with a lower risk of type 2 diabetes; the adjusted odds ratio (OR) for the highest versus the lowest intake was 0.31 (95% confidence interval (CI): 0.21-0.46; P<0.001). An inverse dose-response relationship of similar magnitude was also observed for total isoflavone intake (OR: 0.35; 95% CI: 0.24 to 0.49; P<0.001). In addition, inverse associations of specific soyfoods (soy milk, tofu and mung bean sprout) and major isoflavones (daidzein, genistein and glycitein) with the type 2 diabetes risk were evident.

conclusionsSoyfood and isoflavone intake was associated with a lower type 2 diabetes risk in Vietnamese adults.

Indexed as

Glycine maxAdultAgedCase-Control StudiesDiabetes Mellitus, Type 2Feeding BehaviorFemaleHospitalsHumansIsoflavonesMaleMiddle AgedRisk FactorsSurveys and QuestionnairesVietnamIsoflavones

Identifiers

PMID28488690
OpenAlexW2612555028

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.