ArticleEuropean journal of clinical nutrition2017
An overview of folate status in a population-based study from São Paulo, Brazil and the potential impact of 10 years of national folic acid fortification policy.
Article in European journal of clinical nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Deficiency of B vitamins in women of childbearing age, pregnant, and lactating women in Brazil: a systematic review.Systematic reviews · 2025Pooled it
- Pooled it
- Vitamin B Complex Deficiency After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy-a Systematic Review and Meta-Analysis.Obesity surgery · 2022Pooled it
- Exploring Diet and Nutrient Insufficiencies across Age Groups: Insights from a Population-Based Study of Brazilian Adults.Nutrients · 2024Article
- Prevalence of vitamin B complex deficiencies in women in reproductive age, pregnant, or lactating woman in Brazil: a systematic review and meta-analysis protocol.Systematic reviews · 2023Article
- Folate - a scoping review for Nordic Nutrition Recommendations 2023.Food & nutrition research · 2023Article
- An improved folate stable isotope dilution assay of unexploited food sources from Brazil.Frontiers in nutrition · 2023Article
- Opportunities for diet quality improvement: the potential role of staple grain foods.Public health nutrition · 2021Article
- Dietary folate intake and metabolic syndrome in participants of PREDIMED-Plus study: a cross-sectional study.European journal of nutrition · 2021Article
- Prevalence of inadequate intake of folate after mandatory fortification: results from the first National Dietary Survey in Brazil.European journal of nutrition · 2020Article
- Maternal Haplotypes inGenes · 2019Article
- Dietary Micronutrients Intake Status among Chinese Elderly People Living at Home: Data from CNNHS 2010-2012.Nutrients · 2019Article
- Prevalence and Predictors of Subclinical Micronutrient Deficiency in German Older Adults: Results from the Population-Based KORA-Age Study.Nutrients · 2017Article
- Dietary sources and intakes of folates and vitamin B12 in the Spanish population: Findings from the ANIBES study.PloS one · 2017Article
- It is never too late to rethink serum folate.Hematology, transfusion and cell therapyArticle
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesFood fortification is an important strategy in public health policy for controlling micronutrient malnutrition and a major contributing factor in the eradication of micronutrients' deficiencies. Approximately 50 countries worldwide have adopted food fortification with folic acid (FA). FA fortification of wheat and maize flours has been mandatory in Brazil since 2004. To assess the effect of 10 years of FA food fortification policy on folate status of residents of São Palo, Brazil using a population-based survey. SUBJECTS/
methodsData were from 750 individuals aged ⩾12 years who participated in a cross-sectional population-based survey in São Paulo city, Brazil. Fasting blood samples were collected, and folate was assayed by affinity-high performance liquid chromatografy method with electrochemical detection. The participants provided information about food intake based on two 24 h dietary recall.
resultsOnly 1.76% of population had folate deficiency (<6.8 nmol/l). The mean folate concentration was 29.5 (95% confidence interval: 27.3-31.7) nmol/l for all sex-age groups. The mean folate intake for the population was 375.8 (s.e.m.=6.4) μg/day of dietary folate equivalents (DFEs). When comparing folate intake in DFE from food folate and FA from fortified foods, FA contributed 50% or more of the DFE in almost all sex-age groups. The major contributors of folate intake are processed foods made from wheat flour fortified with FA, especially among subjects younger than 20 years old.
conclusionsThe deficiency of folate is very low, and food fortification contributed to folate intake and had a notable influence on rankings of food contributors of folate.
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