ArticleJournal of sleep research2017
Rest-activity rhythm and sleep characteristics associated with depression symptom severity in strained dementia caregivers.
Article in Journal of sleep research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Moderators of Response to Cognitive Behavior Therapy for Major Depression in Patients With Heart Failure.Psychosomatic medicineTrial
- Enhancing a Behavioral Intervention Using Rest-Activity Rhythm Monitoring via a Consumer Wearable in Older Dementia Caregivers and People With Dementia: Feasibility and Acceptability Study.JMIR formative research · 2026Article
- Sleep and Rest-Activity Rhythms are Delayed and Less Robust in People Living With HIV.Open forum infectious diseases · 2025Article
- Relationship between caregiving burden and alterations in circadian rhythms among spousal caregivers of individuals with cognitive impairment.BMC geriatrics · 2025Article
- Predicting Social Frailty in Older Adults Using Fitbit-Derived Circadian and Heart Rate Biomarkers: Cross-Sectional Study.JMIR formative research · 2025Article
- Wearable sensors for monitoring caregivers of people with dementia: a scoping review.European geriatric medicine · 2025Article
- Rest-Activity Rhythm Patterns and Their Associations With Depression and Obesity: A Study Using Actigraphy and Human-Smartphone Interactions.Depression and anxiety · 2025Article
- Characterization of sleep efficiency transitions in family caregivers.Journal of behavioral medicine · 2024Article
- The bidirectional association of 24-h activity rhythms and sleep with depressive symptoms in middle-aged and elderly persons.Psychological medicine · 2023Article
- A digital health intervention to stabilize the 24-hour rhythm of sleep, meals, and physical activity for reducing depression among older bereaved spouses: Protocol for a randomized controlled trial.Contemporary clinical trials · 2023Article
- Profiles of Accelerometry-Derived Physical Activity Are Related to Perceived Physical Fatigability in Older Adults.Sensors (Basel, Switzerland) · 2021Article
- Timing of Daily Activities over a 24-Hour Period and Affective Status among a National Cohort of Older Dementia Caregivers.Journal of aging and health · 2021Article
- Predictors of Residential Care Admission in Community-Dwelling Older People With Dementia.Journal of the American Medical Directors Association · 2020Observational
- "It's Been a Hard Day's Night": Sleep Problems in Caregivers for Older Adults.Current sleep medicine reports · 2020Article
- Rest-activity rhythms characteristics and seasonal changes in seasonal affective disorder.Chronobiology international · 2018Article
- Rest-activity rhythm profiles associated with manic-hypomanic and depressive symptoms.Journal of psychiatric research · 2018Article
- Sleep disturbances and interrelationship between persons with dementia and family caregivers: The lived experiences of Korean American Dyads.Geriatric nursing (New York, N.Y.)Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Depression is associated with disturbances to sleep and the 24-h sleep-wake pattern (known as the rest-activity rhythm: RAR). However, there remains a need to identify the specific sleep/RAR correlates of depression symptom severity in population subgroups, such as strained dementia caregivers, who are at elevated risk for major depressive disorder. We assessed the cross-sectional associations of sleep/RARs with non-sleep depression symptom severity among 57 (mean age: 74 years, standard deviation: 7.4) strained dementia caregivers who were currently without clinical depression. We derived sleep measures from polysomnography and actigraphy, modelled RARs using a sigmoidally transformed cosine curve and measured non-sleep depression symptom severity using the Hamilton Depression Rating Scale (HRDS) with sleep items removed. The following sleep-wake measures were associated with greater depression symptom severity (absolute Spearman's correlations ranged from 0.23 to 0.32): more time awake after sleep onset (WASO), higher RAR middle level (mesor), relatively shorter active periods (alpha), earlier evening settling time (down-mesor) and less steep RARs (beta). In multivariable analysis, high WASO and low RAR beta were associated independently with depression symptom severity. Predicted non-sleep HDRS means (95% confidence intervals) in caregivers with and without these characteristics were: normal WASO/beta = 3.7 (2.3-5.0), high WASO/normal beta = 5.5 (3.5-7.6), normal WASO/low beta = 6.3 (3.6-8.9) and high WASO/low beta = 8.1 (5.3-10.9). Thus, in our sample of strained caregivers, greater sleep fragmentation (WASO) and less sustained/sharply segregated resting and active periods (low RAR beta) correlate uniquely with depression symptom severity. Longitudinal studies are needed to establish whether these independent sleep-wake correlates of depression symptoms explain heightened depression risk in dementia caregivers.
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