ReviewClinical autonomic research : official journal of the Clinical Autonomic Research Society2017
Autonomic control of body temperature and blood pressure: influences of female sex hormones.
Review in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Sex differences in the impact of extreme heat on cardiovascular disease outcomes: a systematic review and meta-analysis.Environmental health : a global access science source · 2025Pooled it
- Orthostatic-dependent cardiopulmonary responses among trained females during intensity matched resistance exercises in a pilot randomized crossover study.Scientific reports · 2025Trial
- Deep transcranial magnetic stimulation in combination with skin thermography in obesity: a window on sympathetic nervous system.Acta diabetologica · 2022Trial
- Influence of menstrual cycle on autonomic nervous system, muscular strength and mood states.Scientific reports · 2026Article
- Endogenous and exogenous determinants of sex differences in blood pressure.NPJ cardiovascular health · 2026Review
- Local heating increases skin gas acetone content independent of systemic metabolism.Scientific reports · 2026Article
- Temporal trends and disparities in heat-related cardiovascular mortality in the United States (1999-2024): a CDC WONDER analysis.Frontiers in cardiovascular medicine · 2026Article
- Case Report: Perifoveal exudative vascular anomalous complex with secondary fundus hemorrhage.Frontiers in medicine · 2026Article
- Circulating sex hormones, specifically estrogen in females and testosterone in males, are associated with ambient environmental temperature during prolonged physical training.Temperature (Austin, Tex.) · 2026Article
- The relationship between thermophysiology, endocrinology and behaviour in female giant pandas.Scientific reports · 2025Article
- Vascular, inflammatory and perceptual responses to hot water immersion: Impacts of water depth and temperature in young healthy adults.Experimental physiology · 2025Article
- The Menstrual Cycle as a Vital Sign: a comprehensive review.F&S reviews · 2025Article
- The Particularities of Arterial Hypertension in Female Sex: From Pathophysiology to Therapeutic Management.Journal of clinical medicine · 2025Review
- Macular, choroidal and disc associations across women's reproductive life stages: a scoping review from menarche to post-menopause.Eye (London, England) · 2025Article
- Regulation of body temperature and blood pressure in women: Mechanisms and implications for heat illness risk.Experimental physiology · 2025Review
- Association between ambient temperature and non-accidental mortality in Guiyang, China: A time-series analysis (2013-2023).PloS one · 2025Article
- Association between indoor ventilation frequency and frailty among Chinese older adults.Frontiers in public health · 2025Article
- Deep learning model using continuous skin temperature data predicts labor onset.BMC pregnancy and childbirth · 2024Article
- Post-exercise hot or cold water immersion does not alter perception of effort or neuroendocrine responses during subsequent moderate-intensity exercise.Experimental physiology · 2024Article
- Nocturnal heat exposure and stroke risk.European heart journal · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Female reproductive hormones exert important non-reproductive influences on autonomic regulation of body temperature and blood pressure. Estradiol and progesterone influence thermoregulation both centrally and peripherally, where estradiol tends to promote heat dissipation, and progesterone tends to promote heat conservation and higher body temperatures. Changes in thermoregulation over the course of the menstrual cycle and with hot flashes at menopause are mediated by hormonal influences on neural control of skin blood flow and sweating. The influence of estradiol is to promote vasodilation, which, in the skin, results in greater heat dissipation. In the context of blood pressure regulation, both central and peripheral hormonal influences are important as well. Peripherally, the vasodilator influence of estradiol contributes to the lower blood pressures and smaller risk of hypertension seen in young women compared to young men. This is in part due to a mechanism by which estradiol augments beta-adrenergic receptor mediated vasodilation, offsetting alpha-adrenergic vasoconstriction, and resulting in a weak relationship between muscle sympathetic nerve activity and total peripheral resistance, and between muscle sympathetic nerve activity and blood pressure. After menopause, with the loss of reproductive hormones, sympathetic nerve activity, peripheral resistance and blood pressure become more strongly related, and sympathetic nerve activity (which increases with age) becomes a more important contributor to the prevailing level of blood pressure. Continuing to increase our understanding of sex hormone influences on body temperature and blood pressure regulation will provide important insight for optimization of individualized health care for future generations of women.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.