ArticleInternational journal of inflammation2017
Transcriptional and Molecular Pathways Activated in Mesenteric Adipose Tissue and Intestinal Mucosa of Crohn's Disease Patients.
Article in International journal of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Discovery of a novel RSK2 inhibitor for the treatment of metastatic pancreatic cancer.Journal of enzyme inhibition and medicinal chemistry · 2025Article
- Mathematical Models Including microRNA Levels of Mesenteric Adipose Tissue May Predict Postoperative Relapse in Crohn's Disease Patients.Gastro hep advances · 2024Article
- Serial Changes in Body Composition and the Association with Disease Activity during Treatment in Patients with Crohn's Disease.Diagnostics (Basel, Switzerland) · 2022Article
- Visceral adiposity and inflammatory bowel disease.International journal of colorectal disease · 2021Review
- Icariin Inhibits Intestinal Inflammation of DSS-Induced Colitis Mice Through Modulating Intestinal Flora Abundance and Modulating p-p65/p65 Molecule.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021Article
- What was First, Obesity or Inflammatory Bowel Disease? What Does the Gut Microbiota Have to Do with It?Nutrients · 2020Review
- Anatomical Variation in Mesenteric Macrophage Phenotypes in Crohn's Disease.Clinical and translational gastroenterology · 2020Article
- Whole transcriptional analysis identifies markers of B, T and plasma cell signaling pathways in the mesenteric adipose tissue associated with Crohn's disease.Journal of translational medicine · 2020Observational
- The Role of Adipose Tissue in the Pathogenesis and Therapeutic Outcomes of Inflammatory Bowel Disease.Cells · 2019Review
- Article
- Potential Use of Human Stem Cell-Derived Intestinal Organoids to Study Inflammatory Bowel Diseases.Inflammatory bowel diseases · 2018Review
- Dietary Phenethyl Isothiocyanate Protects Mice from Colitis Associated Colon Cancer.International journal of molecular sciences · 2017Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crohn's disease (CD) is a chronic inflammatory disorder, characterized by cytokine imbalance and transcription signaling pathways activation. In addition, the increase of mesenteric adipose tissue (MAT) near the affected intestinal area is a hallmark of CD. Therefore, we evaluated the transcription signaling pathways and cytokines expression in intestinal mucosa and MAT of active CD patients. Ten patients with ileocecal CD and eight with noninflammatory diseases were studied. The biopsies of intestinal mucosa and MAT were snap-frozen and protein expression was determined by immunoblotting. RNA levels were measured by qPCR. The pIkB/IkB ratio and TNF
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.