Evidence map›Paper›PMID 28487682›Full record

ArticleFrontiers in microbiology2017

A Novel Spiro-Heterocyclic Compound Identified by the Silkworm Infection Model Inhibits Transcription in

Atmika Paudel, Hiroshi Hamamoto, Suresh Panthee, Keiichi Kaneko, Shigeki Matsunaga, Motomu Kanai, Yutaka Suzuki, Kazuhisa Sekimizu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Article
  6. Article
  7. Silkworm model forVirulence · 2021
    Article
  8. Review
  9. Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Atmika PaudelInstitute of Medical Mycology, Teikyo UniversityHachioji, Tokyo, Japan.
Hiroshi HamamotoInstitute of Medical Mycology, Teikyo UniversityHachioji, Tokyo, Japan.
Suresh PantheeInstitute of Medical Mycology, Teikyo UniversityHachioji, Tokyo, Japan.
Keiichi KanekoLaboratory of Synthetic Organic Chemistry, Graduate School of Pharmaceutical Sciences, The University of TokyoTokyo, Japan.
Shigeki MatsunagaLaboratory of Synthetic Organic Chemistry, Graduate School of Pharmaceutical Sciences, The University of TokyoTokyo, Japan.
Motomu KanaiLaboratory of Synthetic Organic Chemistry, Graduate School of Pharmaceutical Sciences, The University of TokyoTokyo, Japan.
Yutaka SuzukiDepartment of Medical Genome Science, Graduate School of Frontier Sciences, The University of TokyoKashiwa, Japan.
Kazuhisa SekimizuInstitute of Medical Mycology, Teikyo UniversityHachioji, Tokyo, Japan.
The University of Tokyo · JPTeikyo University · JPSBI Pharmaceuticals (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic compounds are a vital source of antimicrobial agents. To uncover therapeutically effective antimicrobial agents from a chemical library, we screened over 100,000 synthetic compounds for

Indexed as

antimicrobial agentanti-staphylococcalchemical libraryRNA polymerasesigma factorsilkworm infection modeltherapeutic activity

Identifiers

PMID28487682
PMCPMC5403886
OpenAlexW2607772470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.