ArticleFrontiers in human neuroscience2017
Resting-State Neurophysiological Abnormalities in Posttraumatic Stress Disorder: A Magnetoencephalography Study.
Article in Frontiers in human neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Characterizing hippocampal dynamics with MEG: A systematic review and evidence-based guidelines.Human brain mapping · 2019Pooled it
- Attention training modulates resting-state neurophysiological abnormalities in posttraumatic stress disorder.Psychiatry research. Neuroimaging · 2018Trial
- Hippocampal and cortical oscillatory dynamics support semantic processing and performance.Communications biology · 2026Article
- The aftermath of trauma on resting state source-level MEG microstate dynamics.European journal of psychotraumatology · 2025Article
- Spatiotemporal dynamics of multispectral oscillatory activity underlying the processing of negative and positive emotional images.NeuroImage · 2025Article
- Neural Electrical Correlates of Subjective Happiness.Human brain mapping · 2025Article
- Oscillatory brain dynamics underlying affective face processing.Social cognitive and affective neuroscience · 2025Article
- Temporal-Posterior Alpha Power in Resting-State Electroencephalography as a Potential Marker of Complex Childhood Trauma in Institutionalized Adolescents.Brain sciences · 2024Article
- Exploring diet-induced ketosis with exogenous ketone supplementation as a potential intervention in post-traumatic stress disorder: a feasibility study.Frontiers in nutrition · 2024Article
- MEG neural signature of sexual trauma in women veterans with PTSD.Experimental brain research · 2022Article
- Teasing apart trauma: neural oscillations differentiate individual cases of mild traumatic brain injury from post-traumatic stress disorder even when symptoms overlap.Translational psychiatry · 2021Article
- Neurophysiology and Psychopathology Underlying PTSD and Recent Insights into the PTSD Therapies-A Comprehensive Review.Journal of clinical medicine · 2020Review
- Numerical working memory alters alpha-beta oscillations and connectivity in the parietal cortices.Human brain mapping · 2020Article
- Hippocampal and parahippocampal volumes vary by sex and traumatic life events in childrenJournal of psychiatry & neuroscience : JPN · 2020Article
- Resting State Functional Connectivity of the Thalamus in North Korean Refugees with and without Posttraumatic Stress Disorder.Scientific reports · 2020Article
- Intrinsic sensory disinhibition contributes to intrusive re-experiencing in combat veterans.Scientific reports · 2020Article
- Functional reorganization of neural networks involved in emotion regulation following trauma therapy for complex trauma disorders.NeuroImage. Clinical · 2019Article
- Altered default mode network connectivity in adolescents with post-traumatic stress disorder.NeuroImage. Clinical · 2019Article
- Veterans with PTSD demonstrate amygdala hyperactivity while viewing threatening faces: A MEG study.Biological psychology · 2018Article
- Alterations in the Three Components of Selfhood in Persons with Post-Traumatic Stress Disorder Symptoms: A Pilot qEEG Neuroimaging Study.The open neuroimaging journal · 2018Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Posttraumatic stress disorder (PTSD) is a debilitating psychiatric condition that is common in veterans returning from combat operations. While the symptoms of PTSD have been extensively characterized, the neural mechanisms that underlie PTSD are only vaguely understood. In this study, we examined the neurophysiology of PTSD using magnetoencephalography (MEG) in a sample of veterans with and without PTSD. Our primary hypothesis was that veterans with PTSD would exhibit aberrant activity across multiple brain networks, especially those involving medial temporal and frontal regions. To this end, we examined a total of 51 USA combat veterans with a battery of clinical interviews and tests. Thirty-one of the combat veterans met diagnostic criteria for PTSD and the remaining 20 did not have PTSD. All participants then underwent high-density MEG during an eyes-closed resting-state task, and the resulting data were analyzed using a Bayesian image reconstruction method. Our results indicated that veterans with PTSD had significantly stronger neural activity in prefrontal, sensorimotor and temporal areas compared to those without PTSD. Veterans with PTSD also exhibited significantly stronger activity in the bilateral amygdalae, parahippocampal and hippocampal regions. Conversely, healthy veterans had stronger neural activity in the bilateral occipital cortices relative to veterans with PTSD. In conclusion, these data suggest that veterans with PTSD exhibit aberrant neural activation in multiple cortical areas, as well as medial temporal structures implicated in affective processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.