Evidence map›Paper›PMID 28487604›Full record

ArticleWorld journal of gastroenterology2017

Overexpression of fibrinogen-like protein 2 protects against T cell-induced colitis.

Agata Bartczak, Jianhua Zhang, Oyedele Adeyi, Achiya Amir, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Agata BartczakAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
Jianhua ZhangAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
Oyedele AdeyiAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
Achiya AmirAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
David GrantAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
Reginald GorczynskiAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
Nazia SelznerAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
Andrzej ChruscinskiAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
Gary A LevyAgata Bartczak, Jianhua Zhang, David Grant, Reginald Gorczynski, Nazia Selzner, Andrzej Chruscinski, Gary A Levy, Multi Organ Transplant Program, University Health Network, Toronto, Ontario M5G 2C4, Canada.
University Health Network · CAHospital for Sick Children · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the effect of overexpression of fibrinogen-like protein 2 (FGL2) on regulatory T cell (Treg) and effector T (Teff) cell function on T cell-induced colitis in

methodsTreg and Teff cells from

results

conclusionHere we show that

Indexed as

AnimalsCell ProliferationColitisFibrinogenHomeodomain ProteinsMice, Inbred BALB CMice, TransgenicT-Lymphocytes, RegulatoryFgl2 protein, mouseFibrinogenHomeodomain ProteinsRAG-1 proteinColitisFibrinogen-like protein 2Inflammatory bowel diseaseRegulatory T cellsTransgenic mouse

Identifiers

PMID28487604
PMCPMC5403746
OpenAlexW2605961025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.