ArticleWorld journal of gastroenterology2017
Dietary compliance in celiac disease.
Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Testing for Faecal Gluten Immunogenic Peptides: Is It Useful to Evaluate Adherence to Gluten-Free Diet?Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Challenges in the Pediatric Celiac Disease Diagnosis: An Up-to-Date Review.Diagnostics (Basel, Switzerland) · 2025Review
- Review
- Importance of an Ongoing Nutritional Counselling Intervention on Eating Habits of Newly Diagnosed Children with Celiac Disease.Nutrients · 2024Article
- Article
- Systemic consequences of coeliac disease in children with type 1 diabetes - is it worth following a gluten-free diet?Pediatric endocrinology, diabetes, and metabolism · 2024Review
- Population-based screening for celiac disease reveals that the majority of patients are undiagnosed and improve on a gluten-free diet.Scientific reports · 2022Article
- Spontaneous Latency in Adult Patients with Celiac Disease on a Normal Diet after Gluten-Free Diet: Case Series.Middle East journal of digestive diseases · 2022Article
- Spectroscopic investigation of faeces with surface-enhanced Raman scattering: a case study with coeliac patients on gluten-free diet.Analytical and bioanalytical chemistry · 2022Article
- Single-cell approaches to dissect adaptive immune responses involved in autoimmunity: the case of celiac disease.Mucosal immunology · 2022Review
- Expanded Role of a Dietitian in Monitoring a Gluten-Free Diet in Patients with Celiac Disease: Implications for Clinical Practice.Nutrients · 2021Article
- Article
- Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells.The Journal of experimental medicine · 2021Article
- A Portable Gluten Sensor for Celiac Disease Patients May Not Always Be Reliable Depending on the Food and the User.Frontiers in nutrition · 2021Article
- Safety of occasional ingestion of gluten in patients with celiac disease: a real-life study.BMC medicine · 2020Article
- Role of IL-24 in the mucosal remodeling of children with coeliac disease.Journal of translational medicine · 2020Article
- Evaluation of Non-dietary Alternatives for Treatment of Adults With Celiac Disease.Frontiers in nutrition · 2020Article
- Gluten Rhapsody.Nutrients · 2019Article
- Role of Front-of-Package Gluten-Free Product Labeling in a Pair-Matched Study in Women with and without Celiac Disease on a Gluten-Free Diet.Nutrients · 2019Article
- Navigating the Gluten-Free Boom: The Dark Side of Gluten Free Diet.Frontiers in pediatrics · 2019Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease is an immune-mediated disorder that causes severe architectural disturbance in the small intestinal mucosa of genetically-predisposed individuals. Impaired absorption of multiple nutrients results and diarrhea and weight loss develop. Evidence has accumulated that a strict gluten-free diet can result in resolution of diarrhea, weight gain and normalization of nutrient malabsorption. In addition, histopathological changes also normalize, but this histopathological response appears to be time-dependent, sex-dependent and age-dependent. Compliance to a gluten-free diet is difficult and costly resulting in poor compliance and only a limited clinical response. This poses a risk for later long-term complications, including malignancy. A major practical clinical problem is the assessment of compliance to the gluten-free diet. Although symptoms may resolve and serological antibody markers may improve, multiple studies have documented ongoing architectural disturbance and inflammatory change, and with these continued inflammatory changes, a persistent risk for long-term complications. Recent immunological studies have suggested that peptides can be detected in both urine and fecal specimens that may be indicative of limited compliance. At the same time, multiple biopsy studies have demonstrated that complete normalization of the mucosa may occur in some patients within 6 mo of initiation of a gluten-free diet, but more often, up to 2 years or more may be required before repeated biopsies eventually show mucosal recovery and mucosal healing.
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