ArticleScientific reports2017
Oxidative stress biomarkers are associated with visible clinical signs of a disease in frigatebird nestlings.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Herpesvirus Diversity in Atlantic Procellariiformes.Veterinary sciences · 2025Article
- Species-specific physiological status in seabirds: insights from integrating oxidative stress measurements and biologging.Frontiers in physiology · 2025Article
- Measures of Oxidative Status Markers in Relation to Age, Sex, and Season in Sick and Healthy Captive Asian Elephants in Thailand.Animals : an open access journal from MDPI · 2023Article
- Methodological confounds of measuring urinary oxidative stress in wild animals.Ecology and evolution · 2022Article
- A meta-analysis of impacts of immune response and infection on oxidative status in vertebrates.Conservation physiology · 2022Article
- Natural variation in yolk fatty acids, but not androgens, predicts offspring fitness in a wild bird.Frontiers in zoology · 2021Article
- Applied ecoimmunology: using immunological tools to improve conservation efforts in a changing world.Conservation physiology · 2021Article
- Detection and Phylogenetic Characterization of a Novel Herpesvirus in Sooty TernsFrontiers in veterinary science · 2020Article
- Mayaro Virus Induction of Oxidative Stress is Associated With Liver Pathology in a Non-Lethal Mouse Model.Scientific reports · 2019Article
- Physiological costs of infection: herpesvirus replication is linked to blood oxidative stress in equids.Scientific reports · 2018Article
- Extraction Process, Component Analysis, andMediators of inflammation · 2018Article
- Nothing in modern biology makes sense except in the light of ecology and biodiversity conservation.Conservation physiology · 2018Article
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Authors and funding
9 authors at 3 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infectious diseases are one of the most common threats for both domestic and wild animals, but little is known about the effects on the physiological condition and survival of wild animals. Here, we have tested for the first time in a wild vertebrate facing a viral disease possibly due to herpesvirus (i) whether nestlings with either low levels of oxidative damage or high levels of antioxidant protection are less susceptible to develop visible clinical signs, (ii) whether the disease is associated with the nestlings' oxidative status, (iii) whether the association between the disease and oxidative status is similar between males and females (iv), and whether cloacal and tracheal swabs might be used to detect herpesvirus. To address our questions, we took advantage of a population of Magnificent frigatebirds (Fregata magnificens) whose nestlings have experienced high mortality rates in recent times. Our work shows that (i) blood lipid oxidative damage is associated with observable clinical signs and survival probabilities of nestling frigatebirds, and (ii) that high glutathione levels in red blood cells are associated with the emergence of visible clinical signs of the disease. Our work provides evidence that differences in the oxidative status of nestlings might underlie individual health and survival.
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