Evidence map›Paper›PMID 28487352›Full record

ArticleEMBO reports2017

Yi-Wei Chang, Lee A Rettberg, Davi R Ortega, Grant J Jensen

Open access · bronzeAbstract read
In one paragraph

Article in EMBO reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 71 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Science advances · 2025
    Article
  5. Cryo-electron tomography of stationary phasemicroPublication biology · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Structure and Function of the Dot/Icm T4SS.bioRxiv : the preprint server for biology · 2023
    Article
  11. Article
  12. Article
  13. Helical Indexing in Real Space.Scientific reports · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Endogenous membrane stress induces T6SS activity inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yi-Wei ChangCalifornia Institute of Technology, Pasadena, CA, USA.ORCID 0000-0003-2391-473X
Lee A RettbergHoward Hughes Medical Institute, Pasadena, CA, USA.
Davi R OrtegaCalifornia Institute of Technology, Pasadena, CA, USA.
Grant J JensenCalifornia Institute of Technology, Pasadena, CA, USA jensen@caltech.edu.ORCID 0000-0003-1556-4864
California Institute of Technology · USHoward Hughes Medical Institute · US

Funding

Structure and Function of Pathogenesis-Associated Bacterial Structures by Electron CryotomographyR01AI127401 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GRANT J JENSEN · 2016 to 2026
$3.9M
NIAID NIH HHS R01 AI127401
6 · The paper itself

Abstract

The type VI secretion system (T6SS) is a versatile molecular weapon used by many bacteria against eukaryotic hosts or prokaryotic competitors. It consists of a cytoplasmic bacteriophage tail-like structure anchored in the bacterial cell envelope via a cytoplasmic baseplate and a periplasmic membrane complex. Rapid contraction of the sheath in the bacteriophage tail-like structure propels an inner tube/spike complex through the target cell envelope to deliver effectors. While structures of purified contracted sheath and purified membrane complex have been solved, because sheaths contract upon cell lysis and purification, no structure is available for the extended sheath. Structural information about the baseplate is also lacking. Here, we use electron cryotomography to directly visualize intact T6SS structures inside

Indexed as

BacteriophagesCryoelectron MicroscopyIntravital MicroscopyMolecular StructureMyxococcus xanthusProtein BindingProtein MultimerizationType VI Secretion SystemsType VI Secretion Systemsbacterial molecular weaponcontractile bacteriophage tailelectron cryotomographysub‐tomogram averagingtype VI secretion system

Identifiers

PMID28487352
PMCPMC5494534
OpenAlexW2613848270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.