ArticleJournal of medical Internet research2017
Embodied Conversational Agents in Clinical Psychology: A Scoping Review.
Article in Journal of medical Internet research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 16 of them syntheses that pooled it.
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Who cites it
145 citing papers in PubMed, 16 syntheses or guidelines pooled it, 431 citations in OpenAlex.
- Interactive Conversational Agents to Improve Dietary Behaviors for Health Promotion: Mixed Systematic Review.Journal of medical Internet research · 2025Pooled it
- Virtual Health Assistants in Preventive Cancer Care Communication: Systematic Review.JMIR cancer · 2025Pooled it
- Chatbot-Delivered Interventions for Improving Mental Health Among Young People: A Systematic Review and Meta-Analysis.Worldviews on evidence-based nursing · 2025Pooled it
- The uncanny valley effect in embodied conversational agents: a critical systematic review of attractiveness, anthropomorphism, and uncanniness.Frontiers in psychology · 2025Pooled it
- Conversational Agents for Body Weight Management: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Conversational Agent Interventions for Mental Health Problems: Systematic Review and Meta-analysis of Randomized Controlled Trials.Journal of medical Internet research · 2023Pooled it
- Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Effectiveness and acceptability of conversational agents for sexual health promotion: a systematic review and meta-analysis.Sexual health · 2022Pooled it
- The Effectiveness of Artificial Intelligence Conversational Agents in Health Care: Systematic Review.Journal of medical Internet research · 2020Pooled it
- Computer-Controlled Virtual Humans in Patient-Facing Systems: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2020Pooled it
- Effectiveness and Safety of Using Chatbots to Improve Mental Health: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2020Pooled it
- Conversational Agents for Chronic Disease Self-Management: A Systematic Review.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2020Pooled it
- The Personalization of Conversational Agents in Health Care: Systematic Review.Journal of medical Internet research · 2019Pooled it
- Use of Social Robots in Mental Health and Well-Being Research: Systematic Review.Journal of medical Internet research · 2019Pooled it
- Conversational agents in healthcare: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2018Pooled it
- Effectiveness of Virtual Reality for Children and Adolescents with Autism Spectrum Disorder: An Evidence-Based Systematic Review.Sensors (Basel, Switzerland) · 2018Pooled it
- Harnessing large language models in virtual CBT for university students' academic anxiety: a preliminary randomized trial.Frontiers in public health · 2026Trial
- Effects of change in dysfunctional beliefs in avatar-based cognitive therapy for depressive symptoms: a randomized parallel trial.Scientific reports · 2025Trial
- SEE+ computerized classroom-based training enhances 7- to 10-year-olds' socio-emotional cognition through observation and inference.PloS one · 2025Trial
- Text Messaging to Extend School-Based Suicide Prevention: Pilot Randomized Controlled Trial.JMIR mental health · 2024Trial
85 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEmbodied conversational agents (ECAs) are computer-generated characters that simulate key properties of human face-to-face conversation, such as verbal and nonverbal behavior. In Internet-based eHealth interventions, ECAs may be used for the delivery of automated human support factors.
objectiveWe aim to provide an overview of the technological and clinical possibilities, as well as the evidence base for ECA applications in clinical psychology, to inform health professionals about the activity in this field of research.
methodsGiven the large variety of applied methodologies, types of applications, and scientific disciplines involved in ECA research, we conducted a systematic scoping review. Scoping reviews aim to map key concepts and types of evidence underlying an area of research, and answer less-specific questions than traditional systematic reviews. Systematic searches for ECA applications in the treatment of mood, anxiety, psychotic, autism spectrum, and substance use disorders were conducted in databases in the fields of psychology and computer science, as well as in interdisciplinary databases. Studies were included if they conveyed primary research findings on an ECA application that targeted one of the disorders. We mapped each study's background information, how the different disorders were addressed, how ECAs and users could interact with one another, methodological aspects, and the study's aims and outcomes.
resultsThis study included N=54 publications (N=49 studies). More than half of the studies (n=26) focused on autism treatment, and ECAs were used most often for social skills training (n=23). Applications ranged from simple reinforcement of social behaviors through emotional expressions to sophisticated multimodal conversational systems. Most applications (n=43) were still in the development and piloting phase, that is, not yet ready for routine practice evaluation or application. Few studies conducted controlled research into clinical effects of ECAs, such as a reduction in symptom severity.
conclusionsECAs for mental disorders are emerging. State-of-the-art techniques, involving, for example, communication through natural language or nonverbal behavior, are increasingly being considered and adopted for psychotherapeutic interventions in ECA research with promising results. However, evidence on their clinical application remains scarce. At present, their value to clinical practice lies mostly in the experimental determination of critical human support factors. In the context of using ECAs as an adjunct to existing interventions with the aim of supporting users, important questions remain with regard to the personalization of ECAs' interaction with users, and the optimal timing and manner of providing support. To increase the evidence base with regard to Internet interventions, we propose an additional focus on low-tech ECA solutions that can be rapidly developed, tested, and applied in routine practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.