Evidence map›Paper›PMID 28487232›Full record

ReviewFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2017

Potential contribution of insecticide exposure and development of obesity and type 2 diabetes.

Xiao Xiao, John M Clark, Yeonhwa Park

Abstract readReview
In one paragraph

Review in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Article
  8. Metabolic Syndrome and Endocrine Disrupting Chemicals: An Overview of Exposure and Health Effects.International journal of environmental research and public health · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Agrochemicals and obesity.Molecular and cellular endocrinology · 2020
    Review
  14. Review
  15. Longitudinal Study of Metabolic Biomarkers among Conventional and Organic Farmers in Thailand.International journal of environmental research and public health · 2020
    Article
  16. Article
  17. Permethrin and ivermectin modulate lipid metabolism in steatosis-induced HepG2 hepatocyte.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2019
    Article
  18. Article
  19. Permethrin, a pyrethroid insecticide, regulates ERK1/2 activation through membrane depolarization-mediated pathway in HepG2 hepatocytes.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xiao XiaoDepartment of Food Science, University of Massachusetts, Amherst, MA 01003, USA.
John M ClarkDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst 01003, MA, USA.
Yeonhwa ParkDepartment of Food Science, University of Massachusetts, Amherst, MA 01003, USA. Electronic address: ypark@foodsci.umass.edu.
University of Massachusetts Amherst · US

Funding

Role of permethrin in development of obesity and type 2 diabetesR21ES023676 · NIEHS · UNIVERSITY OF MASSACHUSETTS AMHERST · PI PARK, YEONHWA · 2014 to 2015
$416k
NIEHS NIH HHS R21 ES023676
6 · The paper itself

Abstract

The introduction of insecticides has greatly improved agricultural productivity and human nutrition; however, the wide use of insecticides has also sparked growing concern over their health impacts. Increased rate of cancers, neurodegenerative disorders, reproductive dysfunction, birth defects, respiratory diseases, cardiovascular diseases and aging have been linked with insecticide exposure. Meanwhile, a growing body of evidence is suggesting that exposure to insecticides can also potentiate the risk of obesity and type 2 diabetes. This review summarizes the relationship between insecticide exposure and development of obesity and type 2 diabetes using epidemiological and rodent animal studies, including potential mechanisms. The evidence as a whole suggests that exposure to insecticides is linked to increased risk of obesity and type 2 diabetes.

Indexed as

AnimalsDiabetes Mellitus, Type 2Environmental ExposureHumansInsecticidesObesityInsecticidesGlucose metabolismInsecticideObesityType 2 diabetes

Identifiers

PMID28487232
PMCPMC5518693
OpenAlexW2611835135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.