ArticleBehavioural brain research2017
Variant in a common odorant-binding protein gene is associated with bitter sensitivity in people.
Article in Behavioural brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Effect of theFoods (Basel, Switzerland) · 2026Article
- Automated identification of the genetic variants of TAS2R38 bitter taste receptor with supervised learning.Computational and structural biotechnology journal · 2023Article
- Food Neophobia, Odor and Taste Sensitivity, and Overall Flavor Perception in Food.Foods (Basel, Switzerland) · 2021Article
- Molecular and Genetic Factors Involved in Olfactory and Gustatory Deficits and Associations with Microbiota in Parkinson's Disease.International journal of molecular sciences · 2021Review
- Article
- Article
- Obesity and COVID-19: Oro-Naso-Sensory Perception.Journal of clinical medicine · 2020Review
- Electrophysiological Responses from the Human Tongue to the Six Taste Qualities and Their Relationships with PROP Taster Status.Nutrients · 2020Article
- Study of Clinical and Biological Characteristics of Moroccan Covid-19 Patients With and Without Olfactory and/or Gustatory Dysfunction.Frontiers in physiology · 2020Article
- "Smelling and Tasting" Parkinson's Disease: Using Senses to Improve the Knowledge of the Disease.Frontiers in aging neuroscience · 2020Review
- TAS2R38 bitter taste receptor and attainment of exceptional longevity.Scientific reports · 2019Article
- Odorant binding protein 69a connects social interaction to modulation of social responsiveness in Drosophila.PLoS genetics · 2018Article
- Article
- Review
- Fat Sensation: Fatty Acid Taste and Olfaction Sensitivity and the Link with Disinhibited Eating Behaviour.Nutrients · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Deeper understanding of signaling mechanisms underlying bitterness perception in people is essential for designing novel and effective bitter blockers, which could enhance nutrition and compliance with orally administered bitter-tasting drugs. Here we show that variability in a human odorant-binding protein gene, OBPIIa, associates with individual differences in bitterness perception of fat (oleic acid) and of a prototypical bitter stimulus, 6-n-propylthiouracil (PROP), suggesting a novel olfactory role in the modulation of bitterness sensitivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.