Evidence map›Paper›PMID 28486701›Full record

ReviewEpidemiologic reviews2017

Cancer in Transgender People: Evidence and Methodological Considerations.

Hayley Braun, Rebecca Nash, Vin Tangpricha, Janice Brockman, Kevin Ward, Michael Goodman

Open access · bronzeAbstract readReview
In one paragraph

Review in Epidemiologic reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 6 pooled it
21.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 6 syntheses or guidelines pooled it, 205 citations in OpenAlex.

  1. Pooled it
  2. The impact of anal cancer treatment on female sexuality and intimacy: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Hormone therapy and cancer risks in transgender people: a systematic review.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Considerations in Care of the Transgender Orthopedic Patient.Current reviews in musculoskeletal medicine · 2025
    Review
  12. Article
  13. Oncological needs in transgender patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Elevated Risk of Thyroid Malignancy in Biological Males Taking Estrogen Hormone Therapy.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  18. Article
  19. Article
  20. Article

29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hayley Braun
Rebecca Nash
Vin Tangpricha
Janice Brockman
Kevin Ward
Michael Goodman
Emory University · USAtlanta VA Medical Center · US

Funding

Cohort study of mortality and morbidity in transgender personsR21HD076387 · NICHD · EMORY UNIVERSITY · PI GOODMAN, MICHAEL · 2013 to 2014
$451k
NICHD NIH HHS R21 HD076387
6 · The paper itself

Abstract

Transgender people comprise a diverse group of individuals whose gender identity or expression differs from that originally assigned to them at birth. Some, but not all, transgender people elect to undergo medical gender affirmation, which may include therapy with cross-sex hormones and/or surgical change of the genitalia and other sex characteristics. As cross-sex hormones administered for the purposes of gender affirmation may be delivered at high doses and over a period of decades, the carcinogenicity of hormonal therapy in transgender people is an area of considerable concern. In addition, concerns about cancer risk in transgender patients have been linked to sexually transmitted infections, increased exposure to well-known risk factors such as smoking and alcohol use, and the lack of adequate access to screening. Several publications have identified cancer as an important priority in transgender health research and called for large-scale studies. The goals of this article are to summarize the evidence on factors that may differentially affect cancer risk in transgender people, assess the relevant cancer surveillance and epidemiologic data available to date, and offer an overview of possible methodological considerations for future studies investigating cancer incidence and mortality in this population.

Indexed as

Alcohol DrinkingEarly Detection of CancerFemaleGonadal Steroid HormonesHealth Services AccessibilityHumansMaleNeoplasmsRisk FactorsSexually Transmitted DiseasesSmokingTransgender PersonsGonadal Steroid Hormonescancerhormonestransgender

Identifiers

PMID28486701
PMCPMC5868281
OpenAlexW2614036337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.