ArticleAmerican journal of epidemiology2017
Changes in the Inflammatory Potential of Diet Over Time and Risk of Colorectal Cancer in Postmenopausal Women.
Article in American journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Dietary inflammatory index and risk of major digestive tract cancers: a GRADE-assessed systematic review and dose-response meta-analysis.BMC cancer · 2026Pooled it
- Meta-Analysis of the Association between Dietary Inflammatory Index (DII) and Colorectal Cancer.Nutrients · 2022Pooled it
- Medication use and risk of proximal colon cancer: a systematic review of prospective studies with narrative synthesis and meta-analysis.Cancer causes & control : CCC · 2021Pooled it
- Pooled it
- Dietary Inflammatory Potential and Bone Outcomes in Midwestern Post-Menopausal Women.Nutrients · 2023Trial
- Article
- Inflammatory potential of diet and mortality in Australian adults.Public health nutrition · 2024Article
- Changes in Dietary Inflammatory Index Score over Time and Cancer Development in Rural Post-Menopausal Women.Antioxidants (Basel, Switzerland) · 2023Article
- Dietary Inflammatory Index, Obesity, and the Incidence of Colorectal Cancer: Findings from a Hospital-Based Case-Control Study in Malaysia.Nutrients · 2023Article
- Change in the inflammatory potential of diet over 10 years and subsequent mortality: the Multiethnic Cohort Study.The British journal of nutrition · 2023Article
- Dietary Inflammatory Potential and the Risk of Serrated and Adenomatous Colorectal Polyps.Nutrition and cancer · 2023Article
- Dietary inflammatory index and risk of colorectal adenoma: effect measure modification by race, nonsteroidal anti-inflammatory drugs, cigarette smoking and body mass index?Cancer causes & control : CCC · 2021Article
- A new mathematical approach to improve the original dietary inflammatory index (DII) calculation.PloS one · 2021Article
- Post-cancer diagnosis dietary inflammatory potential is associated with survival among women diagnosed with colorectal cancer in the Women's Health Initiative.European journal of nutrition · 2020Article
- The Dietary Inflammatory Index Is Positively Associated with Colorectal Cancer Risk in a Chinese Case-Control Study.Nutrients · 2020Article
- The Role and Mechanism of S1PR5 in Colon Cancer.Cancer management and research · 2020Article
- Secular trends in Dietary Inflammatory Index among adults in the United States, 1999-2014.European journal of clinical nutrition · 2019Article
- Maternal obesity and offspring cognition: the role of inflammation.Pediatric research · 2019Article
- Diet and colon: what matters?Current opinion in gastroenterology · 2019Review
- Association of Dietary Inflammatory Potential With Colorectal Cancer Risk in Men and Women.JAMA oncology · 2018Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
We examined the associations between changes in dietary inflammatory potential and risk of colorectal cancer (CRC) in 87,042 postmenopausal women recruited from 1993-1998 by the Women's Health Initiative, conducted in the United States. Food frequency questionnaire data were used to compute patterns of change in dietary inflammatory index (DII) scores and cumulative average DII scores over 3 years. Cox regression models were used to estimate hazard ratios for CRC risk. After a median of 16.2 years of follow-up, 1,038 CRC cases were diagnosed. DII changes were not substantially associated with overall CRC, but proximal colon cancer risk was higher in the proinflammatory-change DII group than in the antiinflammatory-stable DII group (hazard ratio = 1.32, 95% confidence interval: 1.01, 1.74). Among nonusers of nonsteroidal antiinflammatory drugs (NSAIDs) (Pinteraction = 0.055), the proinflammatory-stable DII group was at increased risk of overall CRC and proximal colon cancer. Also among nonusers of NSAIDs, risks of overall CRC, colon cancer, and proximal colon cancer were higher in the highest quintile compared with the lowest cumulative average DII quintile (65%, 61%, and 91% higher risk, respectively). Dietary changes toward, or a history of, proinflammatory diets are associated with an elevated risk of colon cancer, particularly for proximal colon cancer and among nonusers of NSAIDs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.