Trial reportPloS one2017
Online mindfulness as a promising method to improve exercise capacity in heart disease: 12-month follow-up of a randomized controlled trial.
Trial report in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 20 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Meditation on Bothersome Tinnitus
Mindfulness-Based Cognitive Therapy Delivered Via Group Videoconferencing for Acute Coronary Syndrome Patients With Elevated Depression Symptoms
Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Biomarkers of Response to Internet-Based Psychological Interventions: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Meditation for the primary and secondary prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2024Pooled it
- Psychological interventions for depression in adolescent and adult congenital heart disease.The Cochrane database of systematic reviews · 2023Pooled it
- Engagement Strategies to Improve Adherence and Retention in Web-Based Mindfulness Programs: Systematic Review.Journal of medical Internet research · 2022Pooled it
- Physical activity interventions for people with congenital heart disease.The Cochrane database of systematic reviews · 2020Pooled it
- Trial
- Efficacy of combined hand exercise intervention in patients with chemotherapy-induced peripheral neuropathy: a pilot randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Language-games in live mindfulness-based stress reduction: a philosophy of language analysis of participant-trainer dialogue.Frontiers in psychology · 2026Article
- Online mindfulness interventions in the care of people with physical and mental health conditions: a scoping review.BMJ open · 2025Article
- Article
- Physical Impact of Traditional and Virtual Physical Exercise Programs on Health Outcomes among Corporate Employees.Journal of clinical medicine · 2024Article
- Effects of a maternal psychosocial intervention on hair derived biomarkers of HPA axis function in mothers and children in rural Pakistan.SSM. Mental health · 2022Article
- Videoconference-delivered Mind-Body Resiliency Training in Adults with congenital heart disease: A pilot feasibility trial.International journal of cardiology. Congenital heart disease · 2022Article
- Mindfulness-Based Interventions for Physical and Psychological Wellbeing in Cardiovascular Diseases: A Systematic Review and Meta-Analysis.Brain sciences · 2021Review
- Review
- Relating Instructional Design Components to the Effectiveness of Internet-Based Mindfulness Interventions: A Critical Interpretive Synthesis.Journal of medical Internet research · 2019Review
- Enhancing Social Support Among People with Cardiovascular Disease: a Systematic Scoping Review.Current cardiology reports · 2019Article
- Mindfulness and physical disease: a concise review.Current opinion in psychology · 2019Review
- Digital Characteristics and Dissemination Indicators to Optimize Delivery of Internet-Supported Mindfulness-Based Interventions for People With a Chronic Condition: Systematic Review.JMIR mental health · 2018Review
- Mindful Eco-Wellness: Steps Toward Personal and Planetary Health.Global advances in integrative medicine and healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is increasing evidence that mindfulness can reduce stress, and thereby affect other psychological and physiological outcomes as well. Earlier, we reported the direct 3-month results of an online modified mindfulness-based stress reduction training in patients with heart disease, and now we evaluate the effect at 12-month follow-up. 324 patients (mean age 43.2 years, 53.7% male) were randomized in a 2:1 ratio to additional 3-month online mindfulness training or to usual care alone. The primary outcome was exercise capacity measured with the 6 minute walk test (6MWT). Secondary outcomes were blood pressure, heart rate, respiratory rate, NT-proBNP, cortisol levels (scalp hair sample), mental and physical functioning (SF-36), anxiety and depression (HADS), perceived stress (PSS), and social support (PSSS12). Differences between groups on the repeated outcome measures were analyzed with linear mixed models. At 12-months follow-up, participants showed a trend significant improvement exercise capacity (6MWT: 17.9 meters, p = 0.055) compared to UC. Cohen's D showed significant but small improvement on exercise capacity (d = 0.22; 95%CI 0.05 to 0.39), systolic blood pressure (d = 0.19; 95%CI 0.03 to 0.36), mental functioning (d = 0.22; 95%CI 0.05 to 0.38) and depressive symptomatology (d = 0.18; 95%CI 0.02 to 0.35). All other outcome measures did not change statistically significantly. In the as-treated analysis, systolic blood pressure decreased significantly with 5.5 mmHg (p = 0.045; d = 0.23 (95%CI 0.05-0.41)). Online mindfulness training shows favorable albeit small long-term effects on exercise capacity, systolic blood pressure, mental functioning, and depressive symptomatology in patients with heart disease and might therefore be a beneficial addition to current clinical care.
trial registrationwww.trialregister.nl NTR3453.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.