Evidence map›Paper›PMID 28486173›Full record

ArticleThe Journal of nutritional biochemistry2017

Effects of fish oil supplementation on prostaglandins in normal and tumor colon tissue: modulation by the lipogenic phenotype of colon tumors.

Zora Djuric, Muhammad Nadeem Aslam, Becky R Simon, Ananda Sen, Yan Jiang, Jianwei Ren, Rena Chan, Tanu Soni, T M Rajendiran, William L Smith and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of nutritional biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Dietary Fish Oil Increases the Number of CD11bJournal of inflammation research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Zora DjuricDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: zoralong@umich.edu.
Muhammad Nadeem AslamDepartment of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.
Becky R SimonDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Ananda SenDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Statistics, University of Michigan, Ann Arbor, MI 48109, USA.
Yan JiangDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Jianwei RenDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Rena ChanDepartment of Family Medicine, University of Michigan, Ann Arbor, MI 48109, USA.
Tanu SoniDepartment of Michigan Metabolomics Resource Center, University of Michigan, Ann Arbor, MI 48109, USA.
T M RajendiranDepartment of Michigan Metabolomics Resource Center, University of Michigan, Ann Arbor, MI 48109, USA.
William L SmithDepartment of Biochemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Dean E BrennerDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Pharmacology, University of Michigan, Ann Arbor, MI 48109, USA.
University of Michigan–Ann Arbor · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gary D Luker · 1988 to 2026
$178.2M
Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Translational Research in GI CancerP50CA130810 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BRENNER, DEAN E. · 2010 to 2016
$11.8M
Statistics and Bioinformatics Core - WangU24DK097153 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURANT, CHARLES F · 2012 to 2017
$10.1M
Training Program in Tumor MicroenvironmentT32CA009676 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Maria G Castro, Analisa Virginia DiFeo · 1992 to 2026
$7.3M
NCI NIH HHS P30 CA046592NCI NIH HHS P50 CA130810NCI NIH HHS T32 CA009676NIDDK NIH HHS P30 DK020572NIDDK NIH HHS U24 DK097153
6 · The paper itself

Abstract

Dietary fish oils have potential for prevention of colon cancer, and yet the mechanisms of action in normal and tumor colon tissues are not well defined. Here we evaluated the impact of the colonic fatty acid milieu on the formation of prostaglandins and other eicosanoids. Distal tumors in rats were chemically induced to model inflammatory colonic carcinogenesis. After 21 weeks of feeding with either a fish oil diet containing an eicosapentaenoic acid/ω-6 fatty acid ratio of 0.4 or a Western fat diet, the relationships between colon fatty acids and prostaglandin E

Indexed as

AnimalsBody WeightColonColonic NeoplasmsCyclooxygenase 2Dietary SupplementsDinoprostoneEicosanoidsFatty AcidsFish OilsLipid MetabolismMaleRats, Inbred F344Cyclooxygenase 2DinoprostoneEicosanoidsFatty AcidsFish OilsCancer preventionColon cancerDietFatty acid metabolismProstaglandin E(2)

Identifiers

PMID28486173
PMCPMC5503762
OpenAlexW2607818152

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.