Evidence map›Paper›PMID 28485382›Full record

ArticleImmunology and cell biology2017

Single-cell profiling of lineage determining transcription factors in antigen-specific CD4

Chansavath Phetsouphanh, Yin Xu, Mee Ling Munier, John J Zaunders, Anthony D Kelleher

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunology and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Factoring in CD4 T cells during treatment of HIV.Immunology and cell biology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chansavath PhetsouphanhThe Kirby Institute for Infection and Immunity in Society, University of New South Wales, Kensington, New South Wales, Australia.
Yin XuThe Kirby Institute for Infection and Immunity in Society, University of New South Wales, Kensington, New South Wales, Australia.
Mee Ling MunierThe Kirby Institute for Infection and Immunity in Society, University of New South Wales, Kensington, New South Wales, Australia.
John J ZaundersThe Kirby Institute for Infection and Immunity in Society, University of New South Wales, Kensington, New South Wales, Australia.
Anthony D KelleherThe Kirby Institute for Infection and Immunity in Society, University of New South Wales, Kensington, New South Wales, Australia.
UNSW Sydney · AUSt Vincent’s Private Hospital Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies of protein and gene expression at the single-cell level have revealed that the memory T-cell compartment is more heterogeneous than previously acknowledged. Identifying different T helper subsets involved in memory responses at the single-cell level is thus necessary to understand the level of heterogeneity within this population. Antigen-specific CD4

Indexed as

Cell LineageImmunityAntiretroviral Therapy, Highly ActiveCD4-Positive T-LymphocytesCell ProliferationCytomegalovirusgag Gene Products, Human Immunodeficiency VirusHIV InfectionsHumansImmunologic MemorySingle-Cell AnalysisTetanus ToxinTh1 CellsT-Lymphocytes, RegulatoryTranscription Factorsgag Gene Products, Human Immunodeficiency VirusTetanus ToxinTranscription Factors

Identifiers

PMID28485382
PMCPMC5550558
OpenAlexW2613630570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.