Evidence map›Paper›PMID 28485132›Full record

ArticleJournal of biophotonics2017

Robust numerical phase stabilization for long-range swept-source optical coherence tomography.

Shaozhen Song, Jingjiang Xu, Shaojie Men, Tueng T Shen, Ruikang K Wang

Abstract read
In one paragraph

Article in Journal of biophotonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shaozhen SongUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.
Jingjiang XuUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.
Shaojie MenUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.
Tueng T ShenUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.
Ruikang K WangUniversity of Washington, Department of Bioengineering, Seattle, WA 98195, USA.

Funding

OPTICAL MICROANGIOGRAHY OF CEREBROVASCULAR PERFUSIONR01HL093140 · NHLBI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2008 to 2017
$4.2M
Optical coherence elastography of corneal dynamicsR01EY026532 · NEI · UNIVERSITY OF WASHINGTON · PI SHEN, TUENG T · 2016 to 2020
$2.9M
NON-INVASIVE REAL-TIME LABEL-FREE 3D IMAGING OF RETINAL MICROCIRCULATIONR01EY024158 · NEI · UNIVERSITY OF WASHINGTON · PI WANG, RUIKANG · 2014 to 2017
$1.7M
NEI NIH HHS R01 EY024158NEI NIH HHS R01 EY026532NHLBI NIH HHS R01 HL093140
6 · The paper itself

Abstract

A novel phase stabilization technique is demonstrated with significant improvement in the phase stability of a micro-electromechanical (MEMS) vertical cavity surface-emitting laser (VCSEL) based swept-source optical coherence tomography (SS-OCT) system. Without any requirements of hardware modifications, the new fully numerical phase stabilization technique features high tolerance to acquisition jitter, and significantly reduced budget in computational effort. We demonstrate that when measured with biological tissue, this technique enables a phase sensitivity of 89 mrad in highly scattering tissue, with image ranging distance of up to 12.5 mm at A-line scan rate of 100.3 kHz. We further compare the performances delivered by the phase-stabilization approach with conventional numerical approach for accuracy and computational efficiency. Imaging result of complex signal-based optical coherence tomography angiography (OCTA) and Doppler OCTA indicate that the proposed phase stabilization technique is robust, and efficient in improving the image contrast-to-noise ratio and extending OCTA depth range. The proposed technique can be universally applied to improve phase-stability in generic SS-OCT with different scale of scan rates without a need for special treatment.

Indexed as

AlgorithmsImage Processing, Computer-AssistedLasersModels, TheoreticalTomography, Optical Coherenceoptical coherence tomographyphase-sensitive measurementswept laser

Identifiers

PMID28485132
PMCPMC5831409

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.