Evidence map›Paper›PMID 28484928›Full record

ArticleNeurocritical care2018

Comparison of Quantitative Characteristics of Early Post-resuscitation EEG Between Asphyxial and Ventricular Fibrillation Cardiac Arrest in Rats.

Bihua Chen, Gang Chen, Chenxi Dai, Pei Wang, Lei Zhang, Yuanyuan Huang, Yongqin Li

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Electroencephalographic alpha oscillation as first manifestation of brain restoration after resuscitation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Prognostic Value of EEG in Patients after Cardiac Arrest-An Updated Review.Current neurology and neuroscience reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bihua ChenSchool of Biomedical Engineering, Third Military Medical University, 30 Gaotanyan Main Street, Chongqing, 400038, China.
Gang ChenSchool of Biomedical Engineering, Third Military Medical University, 30 Gaotanyan Main Street, Chongqing, 400038, China.
Chenxi DaiSchool of Biomedical Engineering, Third Military Medical University, 30 Gaotanyan Main Street, Chongqing, 400038, China.
Pei WangSchool of Biomedical Engineering, Third Military Medical University, 30 Gaotanyan Main Street, Chongqing, 400038, China.
Lei ZhangEmergency Department, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China.
Yuanyuan HuangNeurology Department, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China.
Yongqin LiSchool of Biomedical Engineering, Third Military Medical University, 30 Gaotanyan Main Street, Chongqing, 400038, China. leeoken@hotmail.com.ORCID 0000-0002-6114-2382
Army Medical University · CN

Funding

the Author of National Excellent Doctoral Dissertation of China FANEDD201060the National Nature Science Foundation of China NSFC81271656
6 · The paper itself

Abstract

backgroundQuantitative electroencephalogram (EEG) analysis has shown promising results in studying brain injury and functional recovery after cardiac arrest (CA). However, whether the quantitative characteristics of EEG, as potential indicators of neurological prognosis, are influenced by CA causes is unknown. The purpose of this study was designed to compare the quantitative characteristics of early post-resuscitation EEG between asphyxial CA (ACA) and ventricular fibrillation CA (VFCA) in rats.

methodsThirty-two Sprague-Dawley rats of both sexes were randomized into either ACA or VFCA group. Cardiopulmonary resuscitation was initiated after 5-min untreated CA. Characteristics of early post-resuscitation EEG were compared, and the relationships between quantitative EEG features and neurological outcomes were investigated.

resultsCompared with VFCA, serum level of S100B, neurological deficit score and brain histopathologic damage score were dramatically higher in the ACA group. Quantitative measures of EEG, including onset time of EEG burst, time to normal trace, burst suppression ratio, and information quantity, were significantly lower for CA caused by asphyxia and correlated with the 96-h neurological outcome and survival.

conclusionsCharacteristics of earlier post-resuscitation EEG differed between cardiac and respiratory causes. Quantitative measures of EEG not only predicted neurological outcome and survival, but also have the potential to stratify CA with different causes.

Indexed as

Cardiopulmonary ResuscitationElectroencephalographyHeart ArrestAnimalsAsphyxiaDisease Models, AnimalFemaleMaleNervous System DiseasesRandom AllocationRatsRats, Sprague-DawleyVentricular FibrillationAsphyxiaCardiac arrestNeurological outcomeQuantitative EEGVentricular fibrillation

Identifiers

PMID28484928
OpenAlexW2612143655

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.