Evidence map›Paper›PMID 28484843›Full record

ReviewVirchows Archiv : an international journal of pathology2017

HOXB13 a useful marker in pleomorphic giant cell adenocarcinoma of the prostate: a case report and review of the literature.

Laura Larnaudie, Eva Compérat, Pierre Conort, Justine Varinot

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Virchows Archiv : an international journal of pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. HOXB13 is not expressed in pleomorphic giant cell carcinoma of the bladder.Virchows Archiv : an international journal of pathology · 2018
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Laura LarnaudieDepartment of Pathology, Hopital Tenon, AP-HP, UPMC-Paris VI, 4 rue de la Chine, 75020, Paris, France.
Eva CompératDepartment of Pathology, Hopital Tenon, AP-HP, UPMC-Paris VI, 4 rue de la Chine, 75020, Paris, France.
Pierre ConortDepartment of Urology, Hopital Pitie-Salpetriere, AP-HP, UPMC-Paris VI, Paris, France.
Justine VarinotDepartment of Pathology, Hopital Tenon, AP-HP, UPMC-Paris VI, 4 rue de la Chine, 75020, Paris, France. justinevarinot@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of an 81-year-old patient with a pleomorphic giant cell adenocarcinoma of the prostate. After diagnosis, he rapidly developed bone metastasis and died within 1 year. This variant of acinar adenocarcinoma is extremely rare and prognosis is poor. This entity has been included into the 2016 WHO classification. The principal differential diagnosis is urothelial carcinoma. To assess the prostatic origin, routine immunohistochemistry can be problematic. Loss of epitopes in this poorly differentiated entity can occur, such as loss of expression of PSA and p504s. We recently described a very sensitive and specific marker of prostate cancer, HOXB13, which once again has proven to be highly specific and sensitive. This is the first description of a pleomorphic giant cell prostate cancer expressing HOXB13.

Indexed as

Aged, 80 and overBiomarkers, TumorCarcinoma, Acinar CellGiant CellsHomeodomain ProteinsHumansMaleProstatic NeoplasmsBiomarkers, TumorHomeodomain ProteinsHOXB13 protein, humanAdenocarcinomaGiant cellHOXB13PleomorphicProstate cancer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.