ArticleThe Journal of membrane biology2018
Asymmetric Patterns of Small Molecule Transport After Nanosecond and Microsecond Electropermeabilization.
Article in The Journal of membrane biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- The Fascial Capacitor Model: A Biophysical Hypothesis for the Origin of the Local Twitch Response Within Stacking Fascia.International journal of molecular sciences · 2026Article
- Calcium electroporation induces stress response through upregulation of HSP27, HSP70, aspartate β-hydroxylase, and CD133 in human colon cancer cells.Biological research · 2025Article
- Interleaflet Translocation of Second-Harmonic-Generation-Active Dye Molecules in Phospholipid Bilayers with Transmembrane Pores.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Pulsed Electric Field (PEF) Treatment Results in Growth Promotion, Main Flavonoids Extraction, and Phytochemical Profile Modulation ofInternational journal of molecular sciences · 2024Article
- Enhanced Drug Uptake on Application of Electroporation in a Single-Cell Model.The Journal of membrane biology · 2023Article
- Article
- Assessing membrane material properties from the response of giant unilamellar vesicles to electric fields.Advances in physics: X · 2023Article
- Identification of electroporation sites in the complex lipid organization of the plasma membrane.eLife · 2022Article
- Cytotoxicity of a Cell Culture Medium Treated with a High-Voltage Pulse Using Stainless Steel Electrodes and the Role of Iron Ions.Membranes · 2022Article
- Pulse Duration Dependent Asymmetry in Molecular Transmembrane Transport Due to Electroporation in H9c2 Rat Cardiac Myoblast Cells In Vitro.Molecules (Basel, Switzerland) · 2021Article
- Single Cell Forces after Electroporation.ACS nano · 2021Article
- Dye Transport through Bilayers Agrees with Lipid Electropore Molecular Dynamics.Biophysical journal · 2020Article
- Transport of charged small molecules after electropermeabilization - drift and diffusion.BMC biophysics · 2018Article
- Asymmetrical bipolar nanosecond electric pulse widths modify bipolar cancellation.Scientific reports · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Imaging of fluorescent small molecule transport into electropermeabilized cells reveals polarized patterns of entry, which must reflect in some way the mechanisms of the migration of these molecules across the compromised membrane barrier. In some reports, transport occurs primarily across the areas of the membrane nearest the positive electrode (anode), but in others cathode-facing entry dominates. Here we compare YO-PRO-1, propidium, and calcein uptake into U-937 cells after nanosecond (6 ns) and microsecond (220 µs) electric pulse exposures. Each of the three dyes exhibits a different pattern. Calcein shows no preference for anode- or cathode-facing entry that is detectable with our measurement system. Immediately after a microsecond pulse, YO-PRO-1 and propidium enter the cell roughly equally from the positive and negative poles, but transport through the cathode-facing side dominates in less than 1 s. After nanosecond pulse permeabilization, YO-PRO-1 and propidium enter primarily on the anode-facing side of the cell.
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Registered trials
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