ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2018
Necrotizing fasciitis: treatment concepts and clinical results.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 115 citations in OpenAlex.
- Multifocal necrotizing fasciitis: what makes it different? A German trauma center experience.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Exploring Global Research Status and Trends in Necrotizing Fasciitis: A Bibliometric Analysis.The Journal of craniofacial surgery · 2026Article
- Association between procalcitonin and mortality in patients with necrotizing fasciitis: A single-center retrospective study.JPRAS open · 2026Article
- Methicillin-resistantiScience · 2026Review
- A rise in severe necrotizing fasciitis- another consequence of the COVID-19 pandemic?Infection · 2025Article
- Epidemiology and prognostic factors of necrotizing fasciitis in resource-limited regions based on 119 cases.Scientific reports · 2025Article
- Treatment and clinical outcomes in lower extremity necrotizing soft tissue infection.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- Rectum Perforation Complicated Necrotizing Fasciitis Present as Lumbar Disc Herniation: Case Report.Journal of acute medicine · 2025Article
- Consensus on the Diagnosis and Treatment of Adult Necrotizing Fasciitis (2025 Edition).Burns & trauma · 2025Article
- [Necrotizing fasciitis].Chirurgie (Heidelberg, Germany) · 2024Review
- Diagnostic Key Points and Surgical Management of Necrotizing Fasciitis: A Retrospective Study.The international journal of lower extremity wounds · 2024Article
- [Neutrophil-lymphocyte ratio as predictor of mortality in patients with necrotizing fasciitis].Revista medica del Instituto Mexicano del Seguro Social · 2024Observational
- Case report: A rare case of simultaneous necrotizing fasciitis of the breast and forearm.Frontiers in medicine · 2024Article
- Post-procedural necrotizing fasciitis following femoral coronary angiography in patient with chronic endocarditis: A case report.ARYA atherosclerosis · 2024Article
- Giant Ulcer with Necrosis on Right Vulva, Groin, and Thigh-- A Case of Necrotizing Fasciitis Associated with Erythematous Pemphigus.Clinical, cosmetic and investigational dermatology · 2024Article
- Practical Review of Necrotizing Fasciitis: Principles and Evidence-based Management.Plastic and reconstructive surgery. Global open · 2024Review
- [Clinical efficacy of antibiotic bone cement combined with vacuum sealing drainage in treating diabetes mellitus complicated with necrotizing fasciitis].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Observational
- Severe necrotizing soft tissue infections-Is wound microbiology a prognostic factor for clinical outcome?International wound journal · 2023Article
- A successful process of treatment with necrotizing fasciitis of upper extremities in patients with diabetes mellitus: a case report.Annals of medicine and surgery (2012) · 2023Article
- A necrotising fasciitis: case report.Journal of ultrasound · 2023Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNecrotizing fasciitis is a life-threatening soft tissue infection characterized by a rapid spreading infection of the subcutaneous tissue and in particular the fascia. The management of infected tissues requires a rapid diagnosis, immediate aggressive surgical management and an extended debridement. In some cases early amputations of the affected tissues and maximum intensive care treatment, in case of sepsis, are required. Due to a rising number of cases we aimed to evaluate our patients in a retrospective review.
methodAll patients diagnosed with necrotizing fasciitis from 2014 to 2016 (21 months) in our level one trauma center were identified. Their charts were reviewed and data were analyzed in terms of demographic and social information, microbiological results, therapeutic course, socio-economic outcome and mortality.
resultsWe found 15 patients with necrotizing fasciitis. None of these died in the observation period. The mean number of surgical interventions was seven. Two patients underwent limb amputation; diabetes mellitus was assigned with a significant higher risk for amputation. The mean hospitalization was 32 days, including 8 days on intensive care unit. Of the discovered bacteria 93% were sensitive to the initial antibiotic treatment with Ampicillin, Clindamycin and Clont.
conclusionSurgical therapy is indicated if necrotizing fasciitis is suspected. Diabetes mellitus was a clinical predictor of limb amputation in patients with necrotizing fasciitis in our cohort. Aminopenicillin ± sulbactam in combination with clindamycin and/or metronidazole is recommended as initial calculated antibiotic treatment.
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