Evidence map›Paper›PMID 28484459›Full record

ArticleFrontiers in immunology2017

Human Cytomegalovirus-Induced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration.

Linda Grosche, Christina Draßner, Petra Mühl-Zürbes, Lisa Kamm, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Alexander Steinkasserer, Christiane S Heilingloh

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Cytomegalovirus disrupts Lamin A/C to control microtubule-mediated nuclear movement and cell migration.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Journal of virology · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Evasion of the Host Immune Response by Betaherpesviruses.International journal of molecular sciences · 2021
    Review
  9. Review
  10. β2 Integrins-Multi-Functional Leukocyte Receptors in Health and Disease.International journal of molecular sciences · 2020
    Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Linda GroscheDepartment of Immunomodulation, University Hospital Erlangen, Erlangen, Germany.
Christina DraßnerDepartment of Immunomodulation, University Hospital Erlangen, Erlangen, Germany.
Petra Mühl-ZürbesDepartment of Immunomodulation, University Hospital Erlangen, Erlangen, Germany.
Lisa KammDepartment of Immunomodulation, University Hospital Erlangen, Erlangen, Germany.
Vu Thuy Khanh Le-TrillingInstitute for Virology, University Hospital Essen, Essen, Germany.
Mirko TrillingInstitute for Virology, University Hospital Essen, Essen, Germany.
Alexander SteinkassererDepartment of Immunomodulation, University Hospital Erlangen, Erlangen, Germany.
Christiane S HeilinglohDepartment of Immunomodulation, University Hospital Erlangen, Erlangen, Germany.
Universitätsklinikum Erlangen · DEEssen University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As potent antigen-presenting cells, dendritic cells (DCs) are essential for the initiation of effective antiviral immune responses. Viruses and especially herpesviruses, which are able to establish lifelong persistence, exploit several immune evasion mechanisms targeting DC biology. Our group has previously shown that the α-herpesvirus herpes simplex virus type 1 inhibits mature DC (mDC) migration by inducing adhesion

Indexed as

adhesionCYTIPdendritic cellsHCMVmigrationproteasomal degradation

Identifiers

PMID28484459
PMCPMC5399032
OpenAlexW2607669913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.