Evidence map›Paper›PMID 28484051›Full record

ArticleJournal of bacteriology2017

Noncanonical Translation Initiation Comes of Age.

Paul Babitzke, Michael O'Connor

Abstract read
In one paragraph

Article in Journal of bacteriology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paul BabitzkeDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, Pennsylvania State University, University Park, Pennsylvania, USA pxb28@psu.edu oconnormi@umkc.edu.ORCID http://orcid.org/0000-0003-2481-1062
Michael O'ConnorSchool of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri, USA pxb28@psu.edu oconnormi@umkc.edu.

Funding

Mechanism of CsrA-mediated global regulationR01GM059969 · NIGMS · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI BABITZKE, PAUL L, ROMEO, TONY · 1999 to 2021
$7.6M
Regulation of transcription elongationR01GM098399 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI BABITZKE, PAUL L · 2012 to 2024
$3.6M
NIGMS NIH HHS R01 GM059969NIGMS NIH HHS R01 GM098399
6 · The paper itself

Abstract

The canonical translation initiation mechanism involves base pairing between the mRNA and 16S rRNA. However, a variety of identified mechanisms deviate from this conventional route. Beck and Janssen (J Bacteriol 199:e00091-17, 2017, https://doi.org/10.1128/JB.00091-17) have recently described another noncanonical mode of translation initiation. Here, we describe how this process differs from previously reported mechanisms, with the hope that it will foster increased awareness of the diversity of regulatory mechanisms that await discovery.

Indexed as

Bacillus subtilisEscherichia coliGene Expression Regulation, BacterialPeptide Chain Initiation, TranslationalProtein BindingProtein BiosynthesisRNA, BacterialRNA, MessengerRNA, Ribosomal, 16SRNA, BacterialRNA, MessengerRNA, Ribosomal, 16S

Identifiers

PMID28484051
PMCPMC5494744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.