Evidence map›Paper›PMID 28483964›Full record

ArticleAntimicrobial agents and chemotherapy2017

Novel Antibacterial Coating on Orthopedic Wires To Eliminate Pin Tract Infections.

Dmitry Gil, Sergey Shuvaev, Anastasia Frank-Kamenetskii, Vladimir Reukov, Christopher Gross, Alexey Vertegel

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Dmitry GilDepartment of Bioengineering, Clemson University, Clemson, South Carolina, USA.
Sergey ShuvaevDepartment of Chemistry, Durham University, Durham, United Kingdom.
Anastasia Frank-KamenetskiiDepartment of Bioengineering, Clemson University, Clemson, South Carolina, USA.
Vladimir ReukovDepartment of Bioengineering, Clemson University, Clemson, South Carolina, USA.
Christopher GrossDepartment of Orthopedics, Medical University of South Carolina, Charleston, South Carolina, USA.
Alexey VertegelDepartment of Bioengineering, Clemson University, Clemson, South Carolina, USA vertege@clemson.edu.
Clemson University · USDurham University · GBMedical University of South Carolina · US

Funding

Targeted Nano-therapeutics for Neural RegenerationP20GM103444 · NIGMS · CLEMSON UNIVERSITY · PI MARKWALD, ROGER R, VYAVAHARE, NAREN R · 2012 to 2018
$14.9M
NIGMS NIH HHS P20 GM103444
6 · The paper itself

Abstract

Novel approaches to the prevention of microbial infections after the insertion of orthopedic external fixators are in great demand because of the extremely high incidence rates of such infections, which can reach up to 100% with longer implant residence times. Monolaurin is an antimicrobial agent with a known safety record that is broadly used in the food and cosmetic industries; however, its use in antimicrobial coatings of medical devices has not been studied in much detail. Here, we report the use of monolaurin as an antibacterial coating on external fixators for the first time. Monolaurin-coated Kirschner wires (K-wires) showed excellent antibacterial properties against three different bacterial strains, i.e., methicillin-sensitive

Indexed as

Anti-Bacterial AgentsBone WiresCoated Materials, BiocompatibleLauratesMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMonoglyceridesOrthopedic Fixation DevicesProstheses and ImplantsStaphylococcus aureusAnti-Bacterial AgentsCoated Materials, BiocompatibleLauratesMonoglyceridesmonolaurinantibacterial coatingbiofilmsexternal fixatorsmonolaurinorthopedic implants

Identifiers

PMID28483964
PMCPMC5487613
OpenAlexW2612525215

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.