Evidence map›Paper›PMID 28483926›Full record

ArticleMolecular & cellular proteomics : MCP2017

Some Gram-negative Lipoproteins Keep Their Surface Topology When Transplanted from One Species to Another and Deliver Foreign Polypeptides to the Bacterial Surface.

Laura Fantappiè, Carmela Irene, Micaela De Santis, Alessandro Armini, Assunta Gagliardi, Michele Tomasi, Matteo Parri, Valeria Cafardi, Serena Bonomi, Luisa Ganfini and 6 more

Abstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Immunogenicity ofMembranes · 2023
    Article
  5. Article
  6. Heterologous Display ofMembranes · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. CommensalVaccines · 2021
    Article
  11. Article
  12. Article
  13. Article
  14. Proteome-minimized outer membrane vesicles fromJournal of extracellular vesicles · 2021
    Article
  15. Article
  16. Article
  17. Frontiers in microbiology · 2020
    Article
  18. Bacterial outer membrane vesicles engineered with lipidated antigens as a platform forProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Laura FantappièFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Carmela IreneFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Micaela De SantisFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Alessandro Armini§Functional Proteomics Lab., Department of Life Sciences, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Assunta Gagliardi§Functional Proteomics Lab., Department of Life Sciences, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Michele TomasiFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Matteo Parri¶Toscana Life Sciences Scientific Park, Via Fiorentina, 1 53100, Siena, Italy.
Valeria CafardiFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Serena BonomiFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Luisa GanfiniFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Francesca ZerbiniFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Ilaria ZanellaFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy.
Chiara Carnemolla§Functional Proteomics Lab., Department of Life Sciences, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Luca Bini§Functional Proteomics Lab., Department of Life Sciences, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.
Alberto Grandi¶Toscana Life Sciences Scientific Park, Via Fiorentina, 1 53100, Siena, Italy.
Guido GrandiFrom the ‡Synthetic and Structural Vaccinology Unit, CIBIO, University of Trento, Via Sommarive, 9, 38123 Povo, Trento, Italy; guido.grandi@unitn.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Gram-negative bacteria, outer membrane-associated lipoproteins can either face the periplasm or protrude out of the bacterial surface. The mechanisms involved in lipoprotein transport through the outer membrane are not fully elucidated. Some lipoproteins reach the surface by using species-specific transport machinery. By contrast, a still poorly characterized group of lipoproteins appears to always cross the outer membrane, even when transplanted from one organism to another. To investigate such lipoproteins, we tested the expression and compartmentalization in

Indexed as

Aggregatibacter actinomycetemcomitansBacterial Outer Membrane ProteinsCell MembraneEscherichia coliLipoproteinsNeisseria meningitidisProtein TransportRecombinant ProteinsTransformation, BacterialBacterial Outer Membrane ProteinsLipoproteinsRecombinant Proteins

Identifiers

PMID28483926
PMCPMC5500766

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.