ArticleJournal of the American Society of Nephrology : JASN2017
Pregnancy-Induced Sensitization Promotes Sex Disparity in Living Donor Kidney Transplantation.
Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
- Sex and gender as predictors for allograft and patient-relevant outcomes after kidney transplantation.The Cochrane database of systematic reviews · 2024Pooled it
- Reversing pregnancy-induced B cell sensitization to facilitate the induction of transplant tolerance in postpartum recipients.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026Article
- Impact of specialised endocrinology care on metabolic control and healthcare utilisation outcomes after kidney transplantation in patients with diabetes: A 12-month observational cohort study.Diabetes, obesity & metabolism · 2026Observational
- Transplantation and Mortality in Women After Delivering on Hemodialysis.Kidney international reports · 2026Article
- Sex Differences in Alloimmunity and Other Immunological Considerations in Organ Transplantation.Immunological reviews · 2026Review
- A Comparison of Pregnancy Outcomes in Women Receiving Intensive Hemodialysis Versus Kidney Transplant Recipients.Kidney international reports · 2026Article
- The Sex of Donor and Recipients in Solid Organ Transplantation: An in Depth Analysis Across the Council of Europe Member States.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Healthcare workload associated with transition onto kidney replacement therapy: a retrospective cohort study.BMC nephrology · 2025Article
- Women at disadvantage - sex differences in time between dialysis initiation and kidney transplant evaluation or listing: a single-center experience.BMC nephrology · 2025Article
- A Cross-Sectional Social Network Analysis of Decision-Making About Recruiting a Living Donor for Kidney Transplantation.Kidney medicine · 2025Article
- Sex and Gender Disparities in Kidney Transplantation.Advances in kidney disease and health · 2025Review
- B Cell Responses to the Placenta and Fetus.Annual review of pathology · 2025Review
- Lower access to kidney transplantation for women in France is not explained by comorbidities and social deprivation.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024Article
- Fully Understanding Sex/Gender Disparities in Kidney Care Requires End-to-End, National Data Collection.Kidney international reports · 2024Article
- Sex/Gender Disparities in Preemptive Referrals for Kidney Transplantation.Kidney international reports · 2024Article
- Exploring Potential Gender-Based Disparities in Referral for Transplant, Activation on the Waitlist and Kidney Transplantation in a Canadian Cohort.Kidney international reports · 2024Article
- Relationships, race/ethnicity, gender, age, and living kidney donation evaluation willingness.Transplant immunology · 2024Article
- Gender disparities in kidney replacement therapies and transplantation in Colombia.BMC nephrology · 2024Article
- Intersectional race and gender disparities in kidney transplant access in the United States: a scoping review.BMC nephrology · 2024Article
- Sociodemographic Disparities in Adults with Kidney Failure: A Meta-Analysis.Diseases (Basel, Switzerland) · 2024Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of sex disparity in living donor kidney transplantation (LDKT) remains controversial. To determine if women fall behind men in LDKT evaluation, we performed an intention to treat study of 2587 candidates listed for kidney transplant at a single transplant center over 7 years. We found that women and men kidney transplant candidates engaged an equivalent type and number of prospective living donors. However, sex-specific differences in sensitization history and histocompatibility reduced the rate of LDKT for women by 30%. Pregnancy-induced incompatibility with spouse donors was limiting given that spouses were among the individuals most likely to complete donation. Notably, participation in a kidney paired exchange program eliminated sex-based differences in LDKT. Collectively, these data suggest that pregnancy is a formidable biologic barrier for women and contributes uniquely to sex disparity in LDKT. Targeted efforts to improve transplant center participation in paired kidney exchanges may increase sex equity in LDKT.
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Registered trials
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