Evidence map›Paper›PMID 28483675›Full record

ArticleJournal of hepatology2017

Effector CD8

Jessica Fioravanti, Pietro Di Lucia, Diletta Magini, Federica Moalli, Carolina Boni, Alexandre Pierre Benechet, Valeria Fumagalli, Donato Inverso, Andrea Vecchi, Amleto Fiocchi and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. HBV Suppression by Nucleos(t)ide Analogues Reduces PD-1 Expression on Liver-Resident T Cells.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Tissue CD14Nature · 2023
    Article
  15. Neuroprotective effects of interleukin 10 in spinal cord injury.Frontiers in molecular neuroscience · 2023
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Jessica FioravantiDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Pietro Di LuciaDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Diletta MaginiDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Federica MoalliDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy.
Carolina BoniUnit of Infectious Diseases and Hepatology, Azienda Ospedaliero-Universitaria di Parma, 43100 Parma, Italy.
Alexandre Pierre BenechetDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Valeria FumagalliDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Donato InversoDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy.
Andrea VecchiUnit of Infectious Diseases and Hepatology, Azienda Ospedaliero-Universitaria di Parma, 43100 Parma, Italy.
Amleto FiocchiDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Stefan WielandDepartment of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, CA 92037, USA.
Robert PurcellLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Carlo FerrariUnit of Infectious Diseases and Hepatology, Azienda Ospedaliero-Universitaria di Parma, 43100 Parma, Italy.
Francis V ChisariDepartment of Immunology and Microbial Sciences, The Scripps Research Institute, La Jolla, CA 92037, USA.
Luca G GuidottiDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy. Electronic address: guidotti.luca@hsr.it.
Matteo IannaconeDivision of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy; Experimental Imaging Center, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy. Electronic address: iannacone.matteo@hsr.it.
Istituto di Ricovero e Cura a Carattere Scientifico San RaffaeleOspedale di Parma · ITVita-Salute San Raffaele University · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITScripps Research Institute · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimsBesides secreting pro-inflammatory cytokines, chemokines and effector molecules, effector CD8

methodsMouse models of acute HBV pathogenesis, as well as chimpanzees and patients acutely infected with HBV, were used to analyse the role of CD8

resultsMouse HBV-specific effector CD8

conclusionEffector CD8

Indexed as

Acute DiseaseAnimalsApoptosisCD8-Positive T-LymphocytesHepatitis B virusHumansInterleukin-10Interleukin-2LiverMiceMice, Inbred BALB CMice, Inbred C57BLPan troglodytesInterleukin-10Interleukin-2CD8(+) T cellsHepatitis B virusIL-10Liver immunopathology

Identifiers

PMID28483675
PMCPMC7127652
OpenAlexW2611291439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.