ArticleMicrobial cell factories2017
Substrates and oxygen dependent citric acid production by Yarrowia lipolytica: insights through transcriptome and fluxome analyses.
Article in Microbial cell factories, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 91 citations in OpenAlex.
- Acetyl- and malonyl-CoA availability drive EPA selectivity in polyketide synthase-engineered Yarrowia lipolytica.Microbial cell factories · 2026Article
- Revealing systematic changes in the transcriptome during the transition from exponential growth to stationary phase.mSystems · 2025Article
- The evaluation of3 Biotech · 2024Article
- ReprogrammingScience advances · 2024Article
- Transcriptome analysis reveals multiple targets of erythritol-related transcription factor EUF1 in unconventional yeast Yarrowia Lipolytica.Microbial cell factories · 2024Article
- Application of NewInternational journal of molecular sciences · 2024Article
- Article
- Large-Scale Production of Isocitric Acid UsingBiotech (Basel (Switzerland)) · 2023Article
- Genome-wide CRISPR-Cas9 screen reveals a persistent null-hyphal phenotype that maintains high carotenoid production in Yarrowia lipolytica.Biotechnology and bioengineering · 2022Article
- Effect of Nitrogen Concentration on the Biosynthesis of Citric Acid, Protein, and Lipids in the YeastBiomolecules · 2022Article
- Development of Hypertolerant Strain ofACS sustainable chemistry & engineering · 2022Article
- Exploring Yeast Diversity to Produce Lipid-Based Biofuels from Agro-Forestry and Industrial Organic Residues.Journal of fungi (Basel, Switzerland) · 2022Review
- Modelling of the Citric Acid Production from Crude Glycerol by Wild-TypeLife (Basel, Switzerland) · 2022Article
- Review
- Valorisation of xylose to renewable fuels and chemicals, an essential step in augmenting the commercial viability of lignocellulosic biorefineries.Sustainable energy & fuels · 2021Review
- Review
- A Golden-Gate Based Cloning Toolkit to Build Violacein Pathway Libraries inACS synthetic biology · 2021Article
- Fine-tuning mitochondrial activity in Yarrowia lipolytica for citrate overproduction.Scientific reports · 2021Article
- Metabolic Engineering of Non-carotenoid-Producing YeastFrontiers in microbiology · 2021Article
- Analysis ofMetabolic engineering communications · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnlike the well-studied backer yeast where catabolite repression represents a burden for mixed substrate fermentation, Yarrowia lipolytica, an oleaginous yeast, is recognized for its potential to produce single cell oils and citric acid from different feedstocks. These versatilities of Y. lipolytica with regards to substrate utilization make it an attractive host for biorefinery application. However, to develop a commercial process for the production of citric acid by Y. lipolytica, it is necessary to better understand the primary metabolism and its regulation, especially for growth on mixed substrate.
resultsControlling the dissolved oxygen concentration (pO
conclusionUpregulation of most of the genes of the pentose phosphate pathway was found in cultures with highest citrate production with glucose in mono- or in dual substrate fermentation with pO
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