Evidence map›Paper›PMID 28482839›Full record

Trial reportBMC complementary and alternative medicine2017

The effects of Alkanna tinctoria Tausch on split-thickness skin graft donor site management: a randomized, blinded placebo-controlled trial.

Aliasghar Kheiri, Shahideh Amini, Abbas Norouzi Javidan, Mohammad Mehdi Saghafi, Ghasemali Khorasani

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. GenusPlants (Basel, Switzerland) · 2025
    Review
  4. Co-Delivery ofPharmaceutics · 2024
    Article
  5. Heliyon · 2024
    Review
  6. Wound drainage measurements: a narrative review.Archives of dermatological research · 2023
    Review
  7. Metabolite Production inmSystems · 2022
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aliasghar KheiriPlastic and Reconstructive Surgery Division, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Shahideh AminiClinical Pharmacy Department, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Abbas Norouzi JavidanBrain and Spinal Injury Research Center, Institute of Neuroscience, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Mehdi SaghafiPharmacology Department, Faculty of Pharmacy, Iran University of Medical Sciences, Tehran, Iran.
Ghasemali KhorasaniPlastic and Reconstructive Surgery Division, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Gakhorasani@yahoo.com.ORCID http://orcid.org/0000-0001-8608-4919

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA prospective, randomized, placebo-controlled clinical trial was conducted to compare the healing effectiveness of Alkanna tinctoria (L.) Tausch (Boraginaceae) with standard dressing on wound healing at the donor site after removal of the skin graft.

methodsEnrolled patients were randomly allocated to receive topicalA. tinctoria extract ointment (20%) or standard dressing (dressing with base ointment) daily. Wound healing was assessed using the Bates-Jenson assessment tool at the 2

resultsDecreases in wound score were significantly greater in the A. tinctoria group compared with the placebo group (P <0.05). The surface areas of graft donor sites in the A. tinctoria group were significantly reduced as compared with the control group at day 28 of the intervention (P < 0.05). The proportion of patients in the A. tinctoria group achieving complete wound healing within 2 to 4 weeks was 50% and 96.66%, respectively, significantly higher than in patients receiving standard care: 0% and 23.3%, respectively.

conclusionsThis clinical study showed that A. tinctoria dressing accelerates wound healing after graft harvesting.

trial registrationIRCT ID: IRCT201511165781N2 .

Indexed as

AdultBoraginaceaeFemaleHumansMaleMiddle AgedPlant ExtractsProspective StudiesSkin DiseasesSkin TransplantationWound HealingYoung AdultPlant ExtractsAlkannaHealingSkin graftWound

Identifiers

PMID28482839
PMCPMC5422894

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.