ArticlePflugers Archiv : European journal of physiology1988
Potassium and calcium currents and action potentials in mouse Balb/c 3T3 fibroblasts.
Article in Pflugers Archiv : European journal of physiology, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 14 citations in OpenAlex.
- Sustained calcium influx activated by basic fibroblast growth factor in Balb-c 3T3 fibroblasts.The Journal of physiology · 1995Article
- Electrophysiological and immunohistochemical analysis of muscle differentiation in a mouse mesodermal stem cell line.The Journal of physiology · 1991Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The electrical properties of Balb/c 3T3 mouse fibroblasts were studied with the whole-cell patch clamp technique. In current clamp mode a resting potential of -75.5 +/- 2.1 mV was recorded. In voltage clamp mode an inward current was also observed at potentials negative to Vm. This current crossed the 0-current axis at a voltage near Vm, and rectified at more positive potentials; the degree of rectification was dependent on [K+]o. At potentials positive to -30 mV a transient inward current was observed, showing a peak amplitude of -193 +/- 36 pA at +10 mV; the current amplitude was dependent on voltage and [Ca2+]o, it was strongly increased by 20 mM BaCl2 and abolished by 2 microM verapamil and 1 microM nifedipine. These cells, in response to depolarizing stimuli, develop slow action potentials, probably supported by the Ca2+ current.
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