Evidence map›Paper›PMID 28482098›Full record

ArticlePain medicine (Malden, Mass.)2017

The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) Multidimensional Approach to Classifying Acute Pain Conditions.

Michael L Kent, Patrick J Tighe, Inna Belfer, Timothy J Brennan, Stephen Bruehl, Chad M Brummett, Chester C Buckenmaier, Asokumar Buvanendran, Robert I Cohen, Paul Desjardins and 26 more

Abstract read
In one paragraph

Article in Pain medicine (Malden, Mass.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Ibuprofen for acute postoperative pain in children.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Diclofenac for acute postoperative pain in children.The Cochrane database of systematic reviews · 2023
    Pooled it
  4. Trial
  5. Trial
  6. Observational
  7. Article
  8. Article
  9. Suzetrigine, a NaMolecules (Basel, Switzerland) · 2026
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. The genetics of pain.BJA education · 2024
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Michael L KentDepartment of Anesthesiology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Patrick J TigheDepartment of Anesthesiology, College of Medicine, University of Florida, Gainesville, Florida, FL, USA.
Inna BelferFood and Drug Administration, Center for Drug Evaluation and Research, Silver Spring, MD, USA.
Timothy J BrennanDepartment of Anesthesiology, University of Iowa, Iowa City, Iowa, IA, USA.
Stephen BruehlDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, TN, USA.
Chad M BrummettDepartment of Anesthesiology, University of Michigan Health System, Ann Arbor, Michigan, USA.
Chester C BuckenmaierDefense and Veteran's Center for Integrative Pain Management, Uniformed Services University, Bethesda, Maryland, USA.
Asokumar BuvanendranDepartment of Anesthesiology, Rush University Medical Center, Chicago, Illinois, USA.
Robert I CohenDepartment of Anesthesiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
Paul DesjardinsDesjardins Associates LLC, Maplewood, New Jersey, USA.
David EdwardsDepartment of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee, TN, USA.
Roger FillingimCommunity Dentistry and Behavioral Science, University of Florida, Gainesville, Florida, USA.
Jennifer GewandterDepartment of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
Debra B GordonDepartment of Anesthesiology & Pain Medicine, University of Washington, Seattle, USA.
Robert W HurleyDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Henrik KehletSection of Surgical Pathophysiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
John D LoeserDepartment of Anesthesiology & Pain Medicine, University of Washington, Seattle, USA.
Sean MackeyDepartment of Anesthesiology, Perioperative and Pain Medicine, Stanford University, Palo Alto, California, USA.
Samuel A McLeanDepartments of Anesthesiology and Emergency Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Rosemary PolomanoDepartment of Biobehavioral Sciences, University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania, USA.
Siamak RahmanDepartment of Anesthesiology, University of California, Los Angeles, California, USA.
Srinivasa RajaDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Michael RowbothamDepartment of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California, USA.
Santhanam SureshDepartment of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Bernard SchachtelYale School of Public Health, New Haven, Connecticut, USA.
Kristin SchreiberDepartment of Anesthesiology and Pain Management, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Mark SchumacherDepartment of Anesthesia and Perioperative Care, University of California, San Francisco, San Francisco, California, USA.
Brett StaceyCenter for Pain Relief, University of Washington Medical Center, Seattle, Washington, USA.
Steven StanosSwedish Pain Services, Swedish Health System, Seattle, Washington, USA.
Knox ToddGenomic Medicine Institute, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.
Dennis C TurkDepartment of Anesthesiology & Pain Medicine, University of Washington, Seattle, USA.
Steven J WeismanPediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Christopher WuDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Daniel B CarrDepartment of Anesthesiology, Tufts University School of Medicine, Boston, Massachusetts, USA.
Robert H DworkinSchool of Medicine and Dentistry, University of Rochester Medical Center, Rochester, New York, USA.
Gregory TermanDepartment of Anesthesiology & Pain Medicine, University of Washington, Seattle, USA.

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Finding Good TEMporal PostOperative pain Signatures (TEMPOS)R01GM114290 · NIGMS · UNIVERSITY OF FLORIDA · PI TIGHE, PATRICK J · 2015 to 2019
$2.5M
Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) Public-Private PartnershipU01FD005936 · FDA · UNIVERSITY OF ROCHESTER · PI DWORKIN, ROBERT H · 2016 to 2020
$2.5M
FDA HHS U01 FD005936NIA NIH HHS P30 AG028740NIGMS NIH HHS R01 GM114290
6 · The paper itself

Abstract

Objective: With the increasing societal awareness of the prevalence and impact of acute pain, there is a need to develop an acute pain classification system that both reflects contemporary mechanistic insights and helps guide future research and treatment. Existing classifications of acute pain conditions are limiting, with a predominant focus on the sensory experience (e.g., pain intensity) and pharmacologic consumption. Consequently, there is a need to more broadly characterize and classify the multidimensional experience of acute pain. Setting: Consensus report following expert panel involving the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION), American Pain Society (APS), and American Academy of Pain Medicine (AAPM). Methods: As a complement to a taxonomy recently developed for chronic pain, the ACTTION public-private partnership with the US Food and Drug Administration, the APS, and the AAPM convened a consensus meeting of experts to develop an acute pain taxonomy using prevailing evidence. Key issues pertaining to the distinct nature of acute pain are presented followed by the agreed-upon taxonomy. The ACTTION-APS-AAPM Acute Pain Taxonomy will include the following dimensions: 1) core criteria, 2) common features, 3) modulating factors, 4) impact/functional consequences, and 5) putative pathophysiologic pain mechanisms. Future efforts will consist of working groups utilizing this taxonomy to develop diagnostic criteria for a comprehensive set of acute pain conditions. Perspective: The ACTTION-APS-AAPM Acute Pain Taxonomy (AAAPT) is a multidimensional acute pain classification system designed to classify acute pain along the following dimensions: 1) core criteria, 2) common features, 3) modulating factors, 4) impact/functional consequences, and 5) putative pathophysiologic pain mechanisms. Conclusions: Significant numbers of patients still suffer from significant acute pain, despite the advent of modern multimodal analgesic strategies. Mismanaged acute pain has a broad societal impact as significant numbers of patients may progress to suffer from chronic pain. An acute pain taxonomy provides a much-needed standardization of clinical diagnostic criteria, which benefits clinical care, research, education, and public policy. For the purposes of the present taxonomy, acute pain is considered to last up to seven days, with prolongation to 30 days being common. The current understanding of acute pain mechanisms poorly differentiates between acute and chronic pain and is often insufficient to distinguish among many types of acute pain conditions. Given the usefulness of the AAPT multidimensional framework, the AAAPT undertook a similar approach to organizing various acute pain conditions.

Indexed as

AlgorithmsAcute PainEvidence-Based MedicineHumansMedical History TakingPain MeasurementSymptom AssessmentAAAPTAAPTACTTIONAcute PainbiopsychosocialTaxonomy

Identifiers

PMID28482098
PMCPMC5431381

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.