Evidence map›Paper›PMID 28481762›Full record

Observational studyMedical care2017

The Monthly Cycle of Hypoglycemia: An Observational Claims-based Study of Emergency Room Visits, Hospital Admissions, and Costs in a Commercially Insured Population.

Sanjay Basu, Seth A Berkowitz, Hilary Seligman

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Medical care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 76 citations in OpenAlex.

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  12. Journal of the American College of Emergency Physicians open · 2023
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  18. Integrating Produce Prescriptions into the Healthcare System: Perspectives from Key Stakeholders.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sanjay Basu*Department of Medicine and Center for Population Health Sciences, Stanford University, Palo Alto †Harvard Medical School, Center for Primary Care ‡Division of General Internal Medicine and Diabetes Unit, Massachusetts General Hospital, Boston §Department of Medicine, Harvard Medical School ∥Center for Vulnerable Populations, San Francisco General Hospital ¶Departments of Medicine and of Epidemiology and Biostatistics, University of California, San Francisco.
Seth A Berkowitz
Hilary Seligman
Harvard University · USUniversity of California, San Francisco · US

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Cohort filtering models to identify social program effects on health disparitiesDP2MD010478 · NIMHD · STANFORD UNIVERSITY · PI BASU, SANJAY · 2015 to 2015
$2.4M
Understanding & Overcoming Food Insecurity in Diabetes PatientsK23DK109200 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERKOWITZ, SETH A · 2016 to 2020
$973k
NCATS NIH HHS UL1 TR001085NIDDK NIH HHS K23 DK109200NIDDK NIH HHS L30 DK103291NIDDK NIH HHS P30 DK092924NIMHD NIH HHS DP2 MD010478
6 · The paper itself

Abstract

backgroundMultipayer initiatives have sought to address social determinants of health, such as food insecurity, by linking primary care patients to social services. It remains unclear whether such social determinants contribute to avoidable short-term health care costs.

objectivesWe sought to quantify costs and mitigating factors for the increased risk of hypoglycemia at the end of each month among low-income Americans, a phenomenon related to exhaustion of food budgets. RESEARCH

designWe used claims data on 595,770 commercially insured American adults aged 19 through 64 years old from 2004 through 2015 to estimate the risks and costs of emergency room visits and inpatient hospitalizations for hypoglycemia during the last week of each month versus prior weeks.

resultsAlthough persons with household incomes greater than the national median did not experience a monthly cycle of hypoglycemia, those with incomes less than the national median had an odds ratio of 1.07 (95% confidence interval, 1.02-1.12; P=0.005) for emergency room visits or inpatient hospitalizations for hypoglycemia during the last week of each month, compared with earlier weeks. The risk of end-of-the-month hypoglycemia was mitigated to statistical insignificance during a period of increased federal nutrition program benefits from 2009 through 2013. Eliminating the monthly cycle of hypoglycemia among commercially insured nonelderly adults would be expected to avert $54.1 million per year (95% confidence interval, $0.8-$204.0) in emergency department and inpatient hospitalization costs.

conclusionsAddressing the end-of-the-month increase in hypoglycemia risk among lower-income populations may avert substantial costs from emergency department visits and inpatient hospitalizations.

Indexed as

Insurance CoverageInsurance, HealthAdultEmergency Service, HospitalFeasibility StudiesHealth ExpendituresHumansHypoglycemiaInsurance Claim ReviewMiddle AgedPatient AdmissionPrivate SectorRetrospective Studies

Identifiers

PMID28481762
PMCPMC5695234
OpenAlexW2611788484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.