ArticleNutrients2017
Agronomic Approach of Zinc Biofortification Can Increase Zinc Bioavailability in Wheat Flour and thereby Reduce Zinc Deficiency in Humans.
Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 77 citations in OpenAlex.
- Biofortified Yellow-Fleshed Potatoes Provide More Absorbable Zinc than a Commonly Consumed Variety: A Randomized Trial Using Stable Isotopes in Women in the Peruvian Highlands.The Journal of nutrition · 2023Trial
- Common bean exhibits low zinc translocation efficiency to grain under zinc enriched field conditions in Malawi.Discover plants · 2026Article
- Differential effects of sole and phosphorus based nitrogen fertilizer sources on wheat growth and nutrient use efficiency.Scientific reports · 2025Article
- Technologies in Agronomic Biofortification with Zinc in Brazil: A Review.Plants (Basel, Switzerland) · 2025Review
- Optimizing wheat growth and zinc uptake with compost and rice husk in alkaline conditions.BMC plant biology · 2025Article
- Enhancing micronutrient bioavailability in wheat grain through organic fertilizer substitution.Frontiers in nutrition · 2025Article
- Article
- Assessment of Physicochemical Parameters in Two Winegrapes Varieties after Foliar Application of ZnSOPlants (Basel, Switzerland) · 2023Article
- Article
- Agronomic bio-fortification of wheat (Re/views in environmental science and bio/technology · 2023Review
- Zinc Fortification: Current Trends and Strategies.Nutrients · 2022Review
- Enrichment of Grapes with Zinc-Efficiency of Foliar Fertilization with ZnSOPlants (Basel, Switzerland) · 2022Article
- The Potential Impact of Climate Change on the Micronutrient-Rich Food Supply.Advances in nutrition (Bethesda, Md.) · 2022Review
- Increased Provision of Bioavailable Mg through Vegetables Could Significantly Reduce the Growing Health and Economic Burden Caused by Mg Malnutrition.Foods (Basel, Switzerland) · 2021Article
- Severity of zinc and iron malnutrition linked to low intake through a staple crop: a case study in east-central Pakistan.Environmental geochemistry and health · 2021Article
- Source-Sink Manipulation Affects Accumulation of Zinc and Other Nutrient Elements in Wheat Grains.Plants (Basel, Switzerland) · 2021Article
- Multinutrient Biofortification of Maize (Nutrients · 2021Review
- Foliar Zinc Application to Wheat May Lessen the Zinc Deficiency Burden in Rural Quzhou, China.Frontiers in nutrition · 2021Article
- The acceptance of zinc biofortified rice in Latin America: A consumer sensory study and grain quality characterization.PloS one · 2020Article
- Soil Zinc Is Associated with Serum Zinc But Not with Linear Growth of Children in Ethiopia.Nutrients · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zinc (Zn) deficiency is a common disorder of humans in developing countries. The effect of Zn biofortification (via application of six rates of Zn fertilizer to soil) on Zn bioavailability in wheat grain and flour and its impacts on human health was evaluated. Zn bioavailability was estimated with a trivariate model that included Zn homeostasis in the human intestine. As the rate of Zn fertilization increased, the Zn concentration increased in all flour fractions, but the percentages of Zn in standard flour (25%) and bran (75%) relative to total grain Zn were constant. Phytic acid (PA) concentrations in grain and flours were unaffected by Zn biofortification. Zn bioavailability and the health impact, as indicated by disability-adjusted life years (DALYs) saved, increased with the Zn application rate and were greater in standard and refined flour than in whole grain and coarse flour. The biofortified standard and refined flour obtained with application of 50 kg/ha ZnSO₄·7H₂O met the health requirement (3 mg of Zn obtained from 300 g of wheat flour) and reduced DALYs by >20%. Although Zn biofortification increased Zn bioavailability in standard and refined flour, it did not reduce the bioavailability of iron, manganese, or copper in wheat flour.
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