Evidence map›Paper›PMID 28481255›Full record

ArticleMolecules (Basel, Switzerland)2017

In Vitro Anticancer Activity and Structural Characterization of Ubiquinones from Antrodia cinnamomea Mycelium.

I-Chuan Yen, Shih-Yu Lee, Kuen-Tze Lin, Feng-Yi Lai, Mao-Tien Kuo, Wen-Liang Chang

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Safety Assessment ofFoods (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

I-Chuan YenGraduate Institute of Medical Science, National Defense Medical Center, No.116, Sec.6, Minchuan East Road, Neihu District, Taipei 114, Taiwan. yenichuan@mail.ndmctsgh.edu.tw.
Shih-Yu LeeGraduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei 114, Taiwan. leeshihyuno1@mail.ndmctsgh.edu.tw.
Kuen-Tze LinDepartment of Radiation Oncology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan. holyholm@mail.ndmctsgh.edu.tw.
Feng-Yi LaiGraduate Institute of Aerospace and Undersea Medicine, National Defense Medical Center, Taipei 114, Taiwan. rocodo29@hotmail.com.
Mao-Tien KuoLanTyng Biotech, Co, Ltd., Taipei 114, Taiwan. maotien.kuo@gmail.com.
Wen-Liang ChangSchool of Pharmacy, National Defense Medical Center, Taipei 114, Taiwan. wlchang@ndmctsgh.edu.tw.
National Defense Medical Center · TWTri-Service General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new ubiquinones, named antrocinnamone and 4-acetylantrocamol LT3, were isolated along with six known ubiquinones from Antrodia cinnamomea (Polyporaceae) mycelium. The developed HPLC analysis methods successfully identified eight different ubiquinones, two benzenoids, and one maleic acid derivative from A. cinnamomea. The ubiquinones 1-8 exhibited potential and selective cytotoxic activity against three human cancer cell lines, with IC

Indexed as

A549 CellsAntineoplastic AgentsAntrodiaCell CycleCell Line, TumorCell SurvivalCyclohexanonesDrug DiscoveryDrugs, Chinese HerbalHumansMaleatesMyceliumUbiquinone4-hydroxycyclohex-2-enoneAntineoplastic AgentsCyclohexanonesDrugs, Chinese HerbalMaleatesmaleic acidUbiquinone4-acetylantrocamol LT3antrocinnamoneAntrodia cinnamomeacell cyclecytotoxicityflow cytometryHPLC analysis and fingerprintubiquinone derivative

Identifiers

PMID28481255
PMCPMC6154633
OpenAlexW2610516366

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.