Evidence map›Paper›PMID 28481250›Full record

ArticleInternational journal of molecular sciences2017

3D-QSAR, Molecular Docking and Molecular Dynamics Simulation of Pseudomonas aeruginosa LpxC Inhibitors.

Ke Zuo, Li Liang, Wenyi Du, Xin Sun, Wei Liu, Xiaojun Gou, Hua Wan, Jianping Hu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Lipophilic Extracts ofPharmaceuticals (Basel, Switzerland) · 2025
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  7. QSAR Models for Active Substances againstMolecules (Basel, Switzerland) · 2021
    Article
  8. Classification and Design of HIV-1 Integrase Inhibitors Based on Machine Learning.Computational and mathematical methods in medicine · 2021
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ke ZuoCollege of Pharmacy and Biological Engineering, Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China. zuoke2015@outlook.com.
Li LiangCollege of Pharmacy and Biological Engineering, Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China. lianglicdu@163.com.
Wenyi DuCollege of Pharmacy and Biological Engineering, Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China. wydu2017@gmail.com.
Xin SunCollege of Pharmacy and Biological Engineering, Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China. sunbsxw123@163.com.
Wei LiuCollege of Pharmacy and Biological Engineering, Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China. liuwei@cdu.edu.cn.
Xiaojun GouCollege of Pharmacy and Biological Engineering, Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China. gxjmeprd@163.com.
Hua WanCollege of Mathematics and Informatics, South China Agricultural University, Guangzhou 510642, China. wanhua@scau.edu.cn.
Jianping HuCollege of Pharmacy and Biological Engineering, Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu 610106, China. hujianping@emails.bjut.edu.cn.
Chengdu University · CNLeshan Normal University · CNSouth China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an important target for the development of novel antibiotics, UDP-3-

Indexed as

Molecular Docking SimulationMolecular Dynamics SimulationAmidohydrolasesCatalytic DomainEnzyme InhibitorsHydrogen BondingHydroxamic AcidsProtein BindingPseudomonas aeruginosaQuantitative Structure-Activity RelationshipWaterAmidohydrolasesEnzyme InhibitorsHydroxamic AcidsLpxC deacetylase, PseudomonasWater3D-QSARdrug-resistancefree energy landscapeinhibitory mechanismLpxCmethylsulfone hydroxamatemolecular dynamics simulation

Identifiers

PMID28481250
PMCPMC5454807
OpenAlexW2611280806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.